Augmented P22-N31 SEP component in a patient with a unilateral space occupying lesion

• Published in: Electroencephalography and clinical neurophysiology Vol. 88; no. 1; pp. 72 - 76
• Main Authors: Furlong, P.L., Wimalaratna, S., Harding, G.F.A.
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 1993; Amsterdam Elsevier
• Subjects: Aged; Biological and medical sciences; Brain Neoplasms - physiopathology; Brain Neoplasms - secondary; Cortical lesion; Electrodiagnosis. Electric activity recording; Electroencephalography; Evoked Potentials, Somatosensory - physiology; Frontal Lobe - physiopathology; Giant SEP; Hand - innervation; Humans; Investigative techniques, diagnostic techniques (general aspects); Male; Median Nerve - physiopathology; Medical sciences; Nervous system; Neural Pathways - physiopathology; Parietal Lobe - physiopathology; Reaction Time; Somatosensory cortex; Somatosensory evoked potential; Somatosensory cortex; Giant SEP; Cortical lesion; Somatosensory evoked potential; Human; Electrodiagnosis; Nervous system diseases; Space occupying lesion; Craniocerebral; Topography; Cerebral disorder
• ISSN: 0168-5597; 0013-4694; 1872-6380
• DOI: 10.1016/0168-5597(93)90030-S

A patient presented with a right rolandic space occupying lesion resulting in a decrease of position sense, touch and stereognosis in the left upper limb. SEPs revealed an augmentation of the right hemisphere P22 component co-existing with relative attenuation of all other right hemisphere components. The augmented P22-N31 complex represented a ‘giant’ potential in relation to a control group (> 2.5 S.D.). The data provide further evidence that the P22-N31 complex has separate generators from those responsible for the N20-P27-N33 components parietally and P20-N30 components frontally. The focal nature of the lesion and symptomatology are of interest.