Strawberry consumption alleviates doxorubicin-induced toxicity by suppressing oxidative stress
Doxorubicin (Dox), one of the most used chemotherapeutic agents, is known to generate oxidative stress and block DNA synthesis, which result in severe dose-limiting toxicity. A strategy to protect against Dox toxic effects could be to use dietary antioxidants of which fruits and vegetable are a rich...
Saved in:
Published in | Food and chemical toxicology Vol. 94; pp. 128 - 137 |
---|---|
Main Authors | , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
01.08.2016
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Doxorubicin (Dox), one of the most used chemotherapeutic agents, is known to generate oxidative stress and block DNA synthesis, which result in severe dose-limiting toxicity. A strategy to protect against Dox toxic effects could be to use dietary antioxidants of which fruits and vegetable are a rich source. In this context, strawberry consumption is associated with the maintenance of good health and the prevention of several diseases, thanks to the antioxidant capacities of its bioactive compounds. The aim of the present study was to evaluate the protective effects of strawberry consumption against oxidative stress induced by Dox in rats. Animals were fed with strawberry enriched diet (15% of the total calories) for two months and Dox (10 mg/kg; i.p.) was injected at the end of the experimental period. Strawberry consumption significantly inhibited ROS production and oxidative damage biomarkers accumulation in plasma and liver tissue and alleviated histopathological changes in rat livers treated with Dox. The reduction of antioxidant enzyme activities was significantly mitigated after strawberry consumption. In addition, strawberry enriched diet ameliorated liver mitochondrial antioxidant levels and functionality. In conclusion, strawberry intake protects against Dox-induced toxicity, at plasma, liver and mitochondrial levels thanks to its high contents of bioactive compounds.
[Display omitted]
•Strawberry consumption protects against Dox-induced oxidative stress in rats.•Strawberry intake improves antioxidant defences.•Strawberry intake ameliorates mitochondrial antioxidant status and functionality. |
---|---|
AbstractList | Doxorubicin (Dox), one of the most used chemotherapeutic agents, is known to generate oxidative stress and block DNA synthesis, which result in severe dose-limiting toxicity. A strategy to protect against Dox toxic effects could be to use dietary antioxidants of which fruits and vegetable are a rich source. In this context, strawberry consumption is associated with the maintenance of good health and the prevention of several diseases, thanks to the antioxidant capacities of its bioactive compounds. The aim of the present study was to evaluate the protective effects of strawberry consumption against oxidative stress induced by Dox in rats. Animals were fed with strawberry enriched diet (15% of the total calories) for two months and Dox (10 mg/kg; i.p.) was injected at the end of the experimental period. Strawberry consumption significantly inhibited ROS production and oxidative damage biomarkers accumulation in plasma and liver tissue and alleviated histopathological changes in rat livers treated with Dox. The reduction of antioxidant enzyme activities was significantly mitigated after strawberry consumption. In addition, strawberry enriched diet ameliorated liver mitochondrial antioxidant levels and functionality. In conclusion, strawberry intake protects against Dox-induced toxicity, at plasma, liver and mitochondrial levels thanks to its high contents of bioactive compounds.
[Display omitted]
•Strawberry consumption protects against Dox-induced oxidative stress in rats.•Strawberry intake improves antioxidant defences.•Strawberry intake ameliorates mitochondrial antioxidant status and functionality. Doxorubicin (Dox), one of the most used chemotherapeutic agents, is known to generate oxidative stress and block DNA synthesis, which result in severe dose-limiting toxicity. A strategy to protect against Dox toxic effects could be to use dietary antioxidants of which fruits and vegetable are a rich source. In this context, strawberry consumption is associated with the maintenance of good health and the prevention of several diseases, thanks to the antioxidant capacities of its bioactive compounds. The aim of the present study was to evaluate the protective effects of strawberry consumption against oxidative stress induced by Dox in rats. Animals were fed with strawberry enriched diet (15% of the total calories) for two months and Dox (10 mg/kg; i.p.) was injected at the end of the experimental period. Strawberry consumption significantly inhibited ROS production and oxidative damage biomarkers accumulation in plasma and liver tissue and alleviated histopathological changes in rat livers treated with Dox. The reduction of antioxidant enzyme activities was significantly mitigated after strawberry consumption. In addition, strawberry enriched diet ameliorated liver mitochondrial antioxidant levels and functionality. In conclusion, strawberry intake protects against Dox-induced toxicity, at plasma, liver and mitochondrial levels thanks to its high contents of bioactive compounds. Doxorubicin (Dox), one of the most used chemotherapeutic agents, is known to generate oxidative stress and block DNA synthesis, which result in severe dose-limiting toxicity. A strategy to protect against Dox toxic effects could be to use dietary antioxidants of which fruits and vegetable are a rich source. In this context, strawberry consumption is associated with the maintenance of good health and the prevention of several diseases, thanks to the antioxidant capacities of its bioactive compounds. The aim of the present study was to evaluate the protective effects of strawberry consumption against oxidative stress induced by Dox in rats. Animals were fed with strawberry enriched diet (15% of the total calories) for two months and Dox (10 mg/kg; i.p.) was injected at the end of the experimental period. Strawberry consumption significantly inhibited ROS production and oxidative damage biomarkers accumulation in plasma and liver tissue and alleviated histopathological changes in rat livers treated with Dox. The reduction of antioxidant enzyme activities was significantly mitigated after strawberry consumption. In addition, strawberry enriched diet ameliorated liver mitochondrial antioxidant levels and functionality. In conclusion, strawberry intake protects against Dox-induced toxicity, at plasma, liver and mitochondrial levels thanks to its high contents of bioactive compounds. |
Author | Afrin, Sadia Alvarez-Suarez, Jose M. Mezzetti, Bruno Forbes- Hernandez, Tamara Y. Astolfi, Paola Quiles, Josè L. Rubini, Corrado González-Paramás, Ana M. Zizzi, Antonio Santos-Buelga, Celestino Battino, Maurizio Gasparrini, Massimiliano Giampieri, Francesca Bompadre, Stefano |
Author_xml | – sequence: 1 givenname: Francesca surname: Giampieri fullname: Giampieri, Francesca organization: Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy – sequence: 2 givenname: Jose M. surname: Alvarez-Suarez fullname: Alvarez-Suarez, Jose M. organization: Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy – sequence: 3 givenname: Massimiliano surname: Gasparrini fullname: Gasparrini, Massimiliano organization: Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy – sequence: 4 givenname: Tamara Y. surname: Forbes- Hernandez fullname: Forbes- Hernandez, Tamara Y. organization: Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy – sequence: 5 givenname: Sadia surname: Afrin fullname: Afrin, Sadia organization: Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy – sequence: 6 givenname: Stefano surname: Bompadre fullname: Bompadre, Stefano organization: Dipartimento Scienze Biomediche e Sanita’ Pubblica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy – sequence: 7 givenname: Corrado surname: Rubini fullname: Rubini, Corrado organization: Dipartimento Scienze Biomediche e Sanita’ Pubblica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy – sequence: 8 givenname: Antonio surname: Zizzi fullname: Zizzi, Antonio organization: Dipartimento Scienze Biomediche e Sanita’ Pubblica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy – sequence: 9 givenname: Paola surname: Astolfi fullname: Astolfi, Paola organization: Dipartimento Scienze e Ingegneria della Materia, dell’Ambiente ed Urbanistica, Università Politecnica delle Marche, Ancona, Italy – sequence: 10 givenname: Celestino surname: Santos-Buelga fullname: Santos-Buelga, Celestino organization: Grupo de Investigación en Polifenoles (GIP-USAL), Faculty of Pharmacy, Salamanca University, Campus Miguel de Unamuno, E37007, Salamanca, Spain – sequence: 11 givenname: Ana M. surname: González-Paramás fullname: González-Paramás, Ana M. organization: Grupo de Investigación en Polifenoles (GIP-USAL), Faculty of Pharmacy, Salamanca University, Campus Miguel de Unamuno, E37007, Salamanca, Spain – sequence: 12 givenname: Josè L. surname: Quiles fullname: Quiles, Josè L. organization: Departamento de Fisiologia, Instituto de Nutrición y Tecnología de los Alimentos ‘‘José Mataix”, Centro de Investigaciones Biomedicas, Universidad de Granada, Granada, Spain – sequence: 13 givenname: Bruno surname: Mezzetti fullname: Mezzetti, Bruno organization: Dipartimento di Scienze Agrarie, Alimentari e Ambientali, Università Politecnica delle Marche, Ancona, Italy – sequence: 14 givenname: Maurizio orcidid: 0000-0002-7250-1782 surname: Battino fullname: Battino, Maurizio email: m.a.battino@univpm.it organization: Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27286747$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kMlKBDEQhoMoOi4P4EX66KXHLN1JD55E3EDwoF4NWWokQ0_SJunReXszjHoUCmrhr7-o7xDt-uABoVOCpwQTfrGYzk2e0lJOcQnMdtCEdILVnLVkF00wFV3NZ6Q9QIcpLTDGggi-jw6ooB0XjZigt-cc1aeGGNeVCT6NyyG74CvV97ByKkOqbPgKcdTOOF87b0cDtsrhq_R5Xel1lcZhiJCS8-9VGVuV3QqqlDezY7Q3V32Ck598hF5vb16u7-vHp7uH66vH2rCO55pZzGdC0UZbxoA3zGggQDnv2AwboqxomnYmBNOt1QozpSltlemIsIQZ1rAjdL71HWL4GCFluXTJQN8rD2FMknS4KxdIS4uUbKUmhpQizOUQ3VLFtSRYbrDKhSxY5QarxCUwKztnP_ajXoL92_jlWASXWwGUJ1cOokzGgS-oXIRiZoP7x_4bKBCMOg |
CitedBy_id | crossref_primary_10_1016_j_jff_2019_04_037 crossref_primary_10_3390_antiox10010106 crossref_primary_10_3389_fphar_2018_00078 crossref_primary_10_3389_fphar_2018_00232 crossref_primary_10_3233_MNM_17146 crossref_primary_10_1039_C8FO00165K crossref_primary_10_3233_JBR_190390 crossref_primary_10_1016_j_fct_2019_111045 crossref_primary_10_1016_j_phymed_2020_153170 crossref_primary_10_1016_j_fct_2017_01_018 crossref_primary_10_1016_j_fct_2018_08_001 crossref_primary_10_1016_j_tiv_2020_104864 crossref_primary_10_1111_nyas_13373 crossref_primary_10_1186_s13007_019_0421_0 crossref_primary_10_5812_jjcmb_130731 crossref_primary_10_3390_ijms19092842 crossref_primary_10_1007_s00280_019_04019_6 crossref_primary_10_1016_j_fct_2017_11_042 crossref_primary_10_1016_j_ijbiomac_2020_05_224 crossref_primary_10_1016_j_jff_2019_01_015 crossref_primary_10_1155_2020_3971041 crossref_primary_10_3390_nu9030223 crossref_primary_10_1039_C9RA03988K crossref_primary_10_1371_journal_pone_0167484 crossref_primary_10_3390_ijms17101658 crossref_primary_10_1016_j_tiv_2019_06_021 crossref_primary_10_1080_15569543_2018_1559194 crossref_primary_10_3389_fnut_2022_1080147 crossref_primary_10_3390_antiox9020109 crossref_primary_10_1002_jbt_23540 crossref_primary_10_1016_j_biopha_2018_09_171 crossref_primary_10_2174_2212798410666180730095456 crossref_primary_10_1016_j_dib_2017_06_021 crossref_primary_10_1080_19476337_2019_1578267 crossref_primary_10_3390_foods13010110 crossref_primary_10_1016_j_freeradbiomed_2018_07_014 crossref_primary_10_1016_j_sajb_2023_08_066 crossref_primary_10_1093_jpp_rgab129 crossref_primary_10_1016_j_toxlet_2018_02_024 crossref_primary_10_1016_j_foodchem_2017_05_017 crossref_primary_10_1016_j_fct_2018_02_038 |
Cites_doi | 10.1016/j.lwt.2005.09.018 10.1016/j.fct.2010.02.008 10.3233/JBR-130055 10.1017/S1368980011002515 10.1124/pr.56.2.6 10.1021/jf405721d 10.1034/j.1399-3054.2003.00037.x 10.1002/biof.5520090232 10.1016/j.jnutbio.2013.11.002 10.1002/1097-0010(200007)80:9<1307::AID-JSFA638>3.0.CO;2-P 10.1016/0003-2697(76)90527-3 10.1172/JCI118909 10.1016/j.foodchem.2014.01.098 10.1371/journal.pone.0025878 10.1016/S0300-483X(02)00383-9 10.1016/0003-2697(92)90122-N 10.1016/j.nut.2011.08.009 10.1016/S0076-6879(85)13062-4 10.1016/0076-6879(90)86141-H 10.1016/j.foodchem.2011.03.025 10.1016/j.bcp.2014.04.001 10.1016/S0891-5849(98)00315-3 10.1006/abio.1996.0292 10.1021/jf0115589 10.3390/molecules19067798 10.1016/j.yjmcc.2014.11.007 10.1016/j.bpj.2008.10.042 10.1021/jf205065x 10.1024/0300-9831.76.4.178 10.1074/jbc.M508628200 10.1111/j.1440-1681.2007.04717.x 10.1016/j.transproceed.2007.08.091 10.1016/0003-9861(59)90090-6 10.1016/j.mito.2014.10.008 10.1371/journal.pone.0021746 10.1007/s12263-007-0073-y 10.1039/C4FO00048J 10.1016/S0091-679X(08)62030-0 10.1093/jn/123.11.1939 10.1016/j.fct.2010.04.007 10.1016/0014-5793(79)81346-0 10.1039/C5FO00147A 10.1016/S0098-2997(97)00019-8 10.5344/ajev.1977.28.1.49 10.1016/S0076-6879(84)05016-3 10.1016/j.canlet.2007.10.003 10.1016/S0006-291X(05)81429-9 10.1016/j.phrs.2009.05.007 10.1016/S0021-9258(19)42083-8 10.1006/abio.1997.2187 10.1021/jf405455n 10.1080/10715769900301421 10.1002/mnfr.201000220 10.1016/j.freeradbiomed.2006.02.024 |
ContentType | Journal Article |
Copyright | 2016 Elsevier Ltd Copyright © 2016 Elsevier Ltd. All rights reserved. |
Copyright_xml | – notice: 2016 Elsevier Ltd – notice: Copyright © 2016 Elsevier Ltd. All rights reserved. |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7ST 7U7 C1K SOI |
DOI | 10.1016/j.fct.2016.06.003 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Environment Abstracts Toxicology Abstracts Environmental Sciences and Pollution Management Environment Abstracts |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Toxicology Abstracts Environment Abstracts Environmental Sciences and Pollution Management |
DatabaseTitleList | MEDLINE Toxicology Abstracts |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Economics Chemistry Public Health |
EISSN | 1873-6351 |
EndPage | 137 |
ExternalDocumentID | 10_1016_j_fct_2016_06_003 27286747 S0278691516301831 |
Genre | Journal Article |
GroupedDBID | --- --K --M .55 .GJ .~1 0R~ 1B1 1RT 1~. 1~5 29H 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ 9JM AABNK AABVA AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALCJ AALRI AAOAW AAQFI AAQXK AATCM AATLK AAXUO ABFNM ABFRF ABFYP ABGRD ABJNI ABLST ABMAC ABXDB ABYKQ ABZDS ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE ADMUD ADQTV AEBSH AEFWE AEKER AENEX AEQOU AFKWA AFTJW AFXIZ AGHFR AGUBO AGYEJ AHEUO AHHHB AHPSJ AI. AIEXJ AIKHN AITUG AJBFU AJOXV AKIFW ALCLG ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLECG BLXMC CBWCG CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HLV HMT HVGLF HZ~ IHE J1W K-O KCYFY KOM LW9 M34 M41 MO0 N9A O-L O9- OAUVE OGGZJ OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SAB SCC SDF SDG SDP SES SEW SPCBC SPT SSA SSJ SSP SSZ T5K VH1 WUQ X7M ZXP ~G- ~KM AAHBH AAXKI AFJKZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX CITATION 7ST 7U7 C1K SOI |
ID | FETCH-LOGICAL-c386t-3d0697a24bd33e643cbe1e2668390c1ad74459773b5dba03ab225ac817d13c343 |
IEDL.DBID | AIKHN |
ISSN | 0278-6915 |
IngestDate | Fri Aug 16 10:56:20 EDT 2024 Thu Sep 26 18:57:29 EDT 2024 Sat Sep 28 08:19:10 EDT 2024 Fri Feb 23 02:23:44 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Keywords | Oxidative stress ACYs CoQ ALP EPR OGG1 TPC ALT PPH CDNB Doxorubicin TFC Bioactive compounds Strawberry FRAP GSH Pg-3-glc NBT Mitochondrial functionality AST Cy-3-glc GST SOD GR Dox FOX GPx vit A TEAC vit E CAT TAC SEM OCR |
Language | English |
License | Copyright © 2016 Elsevier Ltd. All rights reserved. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c386t-3d0697a24bd33e643cbe1e2668390c1ad74459773b5dba03ab225ac817d13c343 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0002-7250-1782 |
PMID | 27286747 |
PQID | 1808697152 |
PQPubID | 23462 |
PageCount | 10 |
ParticipantIDs | proquest_miscellaneous_1808697152 crossref_primary_10_1016_j_fct_2016_06_003 pubmed_primary_27286747 elsevier_sciencedirect_doi_10_1016_j_fct_2016_06_003 |
PublicationCentury | 2000 |
PublicationDate | August 2016 2016-Aug 2016-08-00 20160801 |
PublicationDateYYYYMMDD | 2016-08-01 |
PublicationDate_xml | – month: 08 year: 2016 text: August 2016 |
PublicationDecade | 2010 |
PublicationPlace | England |
PublicationPlace_xml | – name: England |
PublicationTitle | Food and chemical toxicology |
PublicationTitleAlternate | Food Chem Toxicol |
PublicationYear | 2016 |
Publisher | Elsevier Ltd |
Publisher_xml | – name: Elsevier Ltd |
References | Habig, Pabst, Jacoby (bib28) 1974; 249 Granados-Principal, Quiles, Ramirez-Tortosa, Camacho-Corencia, Sanchez-Rovira, Vera-Ramirez, Ramirez-Tortosa (bib26) 2011; 55 Giampieri, Tulipani, Alvarez-Suarez, L. Quiles, Mezzetti, Battino (bib24) 2012; 28 Quiles, Ramirez-Tortosa, Huertas, Ibañez, Gomez, Battino, Mataix (bib43) 1999; 9 Alvarez-Suarez, Giampieri, Tulipani, Casoli, Di Stefano, González-Paramás, Santos-Buelga, Busco, Quiles, Cordero, Bompadre, Mezzetti, Battino (bib2) 2014; 25 Giampieri, Alvarez-Suarez, Battino (bib19) 2014; 62 Levine, Garland, Oliver, Amici, Climent, Lenz, Ahn, Shaltiel, Stadtman (bib34) 1990; 186 Minotti, Menna, Salvatorelli, Cairo, Gianni (bib39) 2004; 56 Dewanto, Wu, Adom, Liu (bib12) 2002; 50 Giampieri, Forbes-Hernandez, Gasparrini, Alvarez-Suarez, Afrin, Bompadre, Quiles, Mezzetti, Battino (bib23) 2015; 6 Elberry, Abdel-Naim, Abdel-Sattar, Nagy, Mosli, Mohamadin, Ashour (bib14) 2010; 48 Santos, Batista, Caperuto, Costa Rosa (bib48) 2007; 34 Carlberg, Mannervik (bib7) 1985; 113 Giampieri, Alvarez-Suarez, Mazzoni, Forbes-Hernandez, Gasparrini, Gonzalez-Paramas, Santos-Buelga, Quiles, Bompadre, Mezzetti, Battino (bib21) 2014; 5 Jiang, Hunt, Wolff (bib32) 1992; 202 Yamashita, Yamamoto (bib57) 1997; 250 Chandran, Aggarwal, Migrino, Joseph, McAllister, Konorev, Antholine, Zielonka, Srinivasan, Avadhani, Kalyanaraman (bib8) 2009; 96 Quiles, Ramírez-Tortosa, Ibáñez, Alfonso-González, Duthie, Huertas, Mataix (bib44) 1999; 31 Granados-Principal, Quiles, Ramirez-Tortosa, Sanchez-Rovira, Ramirez-Tortosa (bib27) 2010; 48 Rogers, Brand, Petrosyan, Ashok, Elorza, Ferrick, Murphy (bib46) 2011; 6 Giampieri, Alvarez-Suarez, Mazzoni, Forbes-Hernandez, Gasparrini, Gonzàlez-Paramàs, Santos-Buelga, Quiles, Bompadre, Mezzetti, Battino (bib20) 2014; 19 Deighton, Brennan, Finn, Davies (bib11) 2000; 80 Alvarez-Suarez, Dekanski, Ristic, Radonjić, Petronijević, Giampieri, Astolfi, González-Paramás, Santos-Buelga, Tulipani, Quiles, Mezzetti, Battino (bib3) 2011; 6 Xiong, Liu, Lee, Chua, Ho (bib54) 2006; 41 Kakkar, Das, Viswanathan (bib33) 1984; 21 Bradford (bib6) 1976; 72 Diamanti, Mezzetti, Giampieri, Alvarez-Suarez, Quiles, Gonzalez-Alonso, Ramirez-Tortosa Mdel, Granados-Principal, Gonzáles-Paramás, Santos-Buelga, Battino (bib13) 2014; 62 Ellman (bib15) 1959; 82 Forbes-Hernandez, Gasparrini, Afrin, Bompadre, Mezzetti, Quiles, Giampieri, Battino (bib16) 2016; 0 Tulipani, Armeni, Giampieri, Alvarez-Suarez, Gonzalez-Paramás, Santos-Buelga, Busco, Principato, Bompadre, Quiles, Mezzetti, Battino (bib52) 2014; 156 Giampieri, Alvarez-Suarez, Tulipani, Gonzàles-Paramàs, Santos-Buelga, Bompadre, Quiles, Mezzetti, Battino (bib22) 2012; 60 Romandini, Mazzoni, Giampieri, Tulipani, Gasparrini, Forbes-Hernandez, Locorotondo, D’Alessandro, Mezzetti, Bompadre, Alavarez-Suarez (bib47) 2013; 3 Choi, Lee, Kim, Kim, Chi, Kwon, Chun (bib10) 2008; 2 Panov, Dikalov, Shalbuyeva, Taylor, Sherer, Greenamyre (bib40) 2005; 280 Pedersen, Greeawalt, Reynafarje, Hullihen, Decker, Soper, Bustamente (bib41) 1978; 20 Bach-Faig, Berry, Lairon, Reguant, Trichopoulou, Dernini, Medina, Battino, Belahsen, Miranda, Serra-majem (bib4) 2011; 14 Gasparrini, Giampieri, Alvarez-Suarez, Mazzoni, Forbes-Hernandez, Quiles, Bullon, Battino (bib18) 2015; 16 Benzie, Strain (bib5) 1996; 239 Granados-Principal, El-Azem, Pamplona, Ramirez-Tortosa, Pulido-Moran, Vera-Ramirez, Quiles, Sanchez-Rovira, Naudí, Portero-Otin, Perez-Lopez, Ramirez-Tortosa (bib25) 2014; 90 Reeves, Nielsen, Fahey (bib56) 1993; 123 Quiles, Huertas, Battino, Mataix, Ramírez-Tortosa (bib42) 2002; 180 Sies, Koch, Martino, Boveris (bib49) 1979; 103 Mataix, Ochoa, Quiles (bib38) 2006; 76 Watanabe, Owada, Kobayashi, Kawakami, Nagaoka, Murakami, Ishiuchi, Enomoto, Jinnouchi, Sakurai, Tobe, Koizumi, Shimamura, Asakura, Nakano, Otsubo (bib53) 2007; 39 Choi, Kim, Lim, Shin, Lee (bib9) 2008; 259 Yen, Oberley, Vichitbandha, Ho, St Clair (bib55) 1996; 98 Slinkard, Singleton (bib50) 1997; 28 Tulipani, Alvarez-Suarez, Busco, Bompadre, Quiles, Mezzetti, Battino (bib51) 2011; 128 Gao, Li, Feng, Li, Liu, Cai, Lu, Huang, Wang, Li, Chen, Ye, Liu (bib17) 2015; 79 Marques-Aleixo, Santos-Alves, Mariani, Rizo-Roca, Padrão, Rocha-Rodrigues, Viscor, Torrella, Ferreira, Oliveira, Magalhães, Ascensão (bib36) 2015; 20 Lopes da Silva, Escribano-Bailon, Perez Alonso, Rivas-Gonzalo, Santos-Buelga (bib35) 2007; 40 Mataix, Mañas, Quiles, Battino, Cassinello, Lopez-Frias, Huertas (bib37) 1997; 18 Aebi (bib1) 1984; 105 Helsper, de Vos, Maas, Jonker, Van Den Broeck, Jordi, Pot, Keizer, Schapendonk (bib29) 2003; 117 Ibrahim, Ashour, Ibrahim, El-Bitar, Gomaa, Abdel-Rahim (bib31) 2009; 60 Huertas, Battino, Mataix, Lenaz (bib30) 1991; 181 Re, Pellegrini, Proteggente, Pannala, Yang, Rice-Evans (bib45) 1999; 26 Giampieri (10.1016/j.fct.2016.06.003_bib20) 2014; 19 Pedersen (10.1016/j.fct.2016.06.003_bib41) 1978; 20 Re (10.1016/j.fct.2016.06.003_bib45) 1999; 26 Aebi (10.1016/j.fct.2016.06.003_bib1) 1984; 105 Alvarez-Suarez (10.1016/j.fct.2016.06.003_bib3) 2011; 6 Reeves (10.1016/j.fct.2016.06.003_bib56) 1993; 123 Romandini (10.1016/j.fct.2016.06.003_bib47) 2013; 3 Gasparrini (10.1016/j.fct.2016.06.003_bib18) 2015; 16 Quiles (10.1016/j.fct.2016.06.003_bib44) 1999; 31 Yen (10.1016/j.fct.2016.06.003_bib55) 1996; 98 Dewanto (10.1016/j.fct.2016.06.003_bib12) 2002; 50 Lopes da Silva (10.1016/j.fct.2016.06.003_bib35) 2007; 40 Giampieri (10.1016/j.fct.2016.06.003_bib21) 2014; 5 Benzie (10.1016/j.fct.2016.06.003_bib5) 1996; 239 Mataix (10.1016/j.fct.2016.06.003_bib37) 1997; 18 Deighton (10.1016/j.fct.2016.06.003_bib11) 2000; 80 Granados-Principal (10.1016/j.fct.2016.06.003_bib27) 2010; 48 Granados-Principal (10.1016/j.fct.2016.06.003_bib26) 2011; 55 Chandran (10.1016/j.fct.2016.06.003_bib8) 2009; 96 Slinkard (10.1016/j.fct.2016.06.003_bib50) 1997; 28 Huertas (10.1016/j.fct.2016.06.003_bib30) 1991; 181 Diamanti (10.1016/j.fct.2016.06.003_bib13) 2014; 62 Choi (10.1016/j.fct.2016.06.003_bib9) 2008; 259 Tulipani (10.1016/j.fct.2016.06.003_bib51) 2011; 128 Gao (10.1016/j.fct.2016.06.003_bib17) 2015; 79 Marques-Aleixo (10.1016/j.fct.2016.06.003_bib36) 2015; 20 Watanabe (10.1016/j.fct.2016.06.003_bib53) 2007; 39 Ibrahim (10.1016/j.fct.2016.06.003_bib31) 2009; 60 Granados-Principal (10.1016/j.fct.2016.06.003_bib25) 2014; 90 Habig (10.1016/j.fct.2016.06.003_bib28) 1974; 249 Helsper (10.1016/j.fct.2016.06.003_bib29) 2003; 117 Bach-Faig (10.1016/j.fct.2016.06.003_bib4) 2011; 14 Kakkar (10.1016/j.fct.2016.06.003_bib33) 1984; 21 Xiong (10.1016/j.fct.2016.06.003_bib54) 2006; 41 Giampieri (10.1016/j.fct.2016.06.003_bib24) 2012; 28 Sies (10.1016/j.fct.2016.06.003_bib49) 1979; 103 Ellman (10.1016/j.fct.2016.06.003_bib15) 1959; 82 Quiles (10.1016/j.fct.2016.06.003_bib42) 2002; 180 Yamashita (10.1016/j.fct.2016.06.003_bib57) 1997; 250 Choi (10.1016/j.fct.2016.06.003_bib10) 2008; 2 Tulipani (10.1016/j.fct.2016.06.003_bib52) 2014; 156 Giampieri (10.1016/j.fct.2016.06.003_bib23) 2015; 6 Giampieri (10.1016/j.fct.2016.06.003_bib19) 2014; 62 Panov (10.1016/j.fct.2016.06.003_bib40) 2005; 280 Minotti (10.1016/j.fct.2016.06.003_bib39) 2004; 56 Elberry (10.1016/j.fct.2016.06.003_bib14) 2010; 48 Forbes-Hernandez (10.1016/j.fct.2016.06.003_bib16) 2016; 0 Alvarez-Suarez (10.1016/j.fct.2016.06.003_bib2) 2014; 25 Jiang (10.1016/j.fct.2016.06.003_bib32) 1992; 202 Carlberg (10.1016/j.fct.2016.06.003_bib7) 1985; 113 Rogers (10.1016/j.fct.2016.06.003_bib46) 2011; 6 Bradford (10.1016/j.fct.2016.06.003_bib6) 1976; 72 Santos (10.1016/j.fct.2016.06.003_bib48) 2007; 34 Giampieri (10.1016/j.fct.2016.06.003_bib22) 2012; 60 Levine (10.1016/j.fct.2016.06.003_bib34) 1990; 186 Mataix (10.1016/j.fct.2016.06.003_bib38) 2006; 76 Quiles (10.1016/j.fct.2016.06.003_bib43) 1999; 9 |
References_xml | – volume: 31 start-page: 129 year: 1999 end-page: 135 ident: bib44 article-title: Vitamin E supplementation increases the stability and the in vivo antioxidant capacity of refined olive oil publication-title: Free Radic. Res. contributor: fullname: Mataix – volume: 72 start-page: 248 year: 1976 end-page: 254 ident: bib6 article-title: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding publication-title: Anal. Biochem. contributor: fullname: Bradford – volume: 48 start-page: 1178 year: 2010 end-page: 1184 ident: bib14 article-title: Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats publication-title: Food Chem. Toxicol. contributor: fullname: Ashour – volume: 128 start-page: 180 year: 2011 end-page: 186 ident: bib51 article-title: Strawberry consumption improves plasma antioxidant status and erythrocyte resistance to oxidative haemolysis in humans publication-title: Food Chem. contributor: fullname: Battino – volume: 39 start-page: 3002 year: 2007 end-page: 3006 ident: bib53 article-title: Protective effects of MnM2Py4P and Mn-salen against small bowel ischemia/reperfusion injury in rats using an in vivo and an ex vivo electron paramagnetic resonance technique with a spin probe publication-title: Transpl. Proc. contributor: fullname: Otsubo – volume: 250 start-page: 66 year: 1997 end-page: 73 ident: bib57 article-title: Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress publication-title: Anal. Biochem. contributor: fullname: Yamamoto – volume: 90 start-page: 25 year: 2014 end-page: 33 ident: bib25 article-title: Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer publication-title: Biochem. Pharmacol. contributor: fullname: Ramirez-Tortosa – volume: 5 start-page: 1939 year: 2014 end-page: 1948 ident: bib21 article-title: An anthocyanin-rich strawberry extract protects against oxidative stress damage and improves mitochondrial functionality in human dermal fibroblasts exposed to an oxidizing agent publication-title: Food Funct. contributor: fullname: Battino – volume: 40 start-page: 374 year: 2007 end-page: 382 ident: bib35 article-title: Anthocyanin pigments in strawberry publication-title: LWT-Food Scien. Tech. contributor: fullname: Santos-Buelga – volume: 18 start-page: S129 year: 1997 end-page: S135 ident: bib37 article-title: Coenzyme Q content depends upon oxidative stress and dietary fat unsaturation publication-title: Mol. Asp. Med. contributor: fullname: Huertas – volume: 6 start-page: 1386 year: 2015 end-page: 1398 ident: bib23 article-title: Strawberry as a health promoter: an evidence based review publication-title: Food Funct. contributor: fullname: Battino – volume: 55 start-page: S117 year: 2011 end-page: S126 ident: bib26 article-title: Hydroxytyrosol inhibits growth and cell proliferation and promotes high expression of sfrp4 in rat mammary tumours publication-title: Mol. Nutr. Food Res. contributor: fullname: Ramirez-Tortosa – volume: 103 start-page: 287 year: 1979 end-page: 290 ident: bib49 article-title: Increased biliary glutathione disulfide release in chronically ethanol treated rats publication-title: FEBS Lett. contributor: fullname: Boveris – volume: 60 start-page: 2322 year: 2012 end-page: 2327 ident: bib22 article-title: Photoprotective potential of strawberry (Fragaria× ananassa) extract against UV-A irradiation damage on human fibroblasts publication-title: J. Agric. Food Chem. contributor: fullname: Battino – volume: 105 start-page: 121 year: 1984 end-page: 126 ident: bib1 article-title: Catalase in vitro publication-title: Methods Enzymol. contributor: fullname: Aebi – volume: 41 start-page: 46 year: 2006 end-page: 55 ident: bib54 article-title: Attenuation of doxorubicin induced contractile and mitochondrial dysfunction in mouse heart by cellular glutathione peroxidase publication-title: Free Radic. Biol. Med. contributor: fullname: Ho – volume: 20 start-page: 411 year: 1978 end-page: 481 ident: bib41 article-title: Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues publication-title: Methods Cell. Biol. contributor: fullname: Bustamente – volume: 239 start-page: 70 year: 1996 end-page: 76 ident: bib5 article-title: Ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: the FRAP assay publication-title: Anal. Biochem. contributor: fullname: Strain – volume: 50 start-page: 3010 year: 2002 end-page: 3014 ident: bib12 article-title: Thermal processing enhances the nutritional values of tomatoes by increasing the total antioxidant activity publication-title: J. Agric. Food Chem. contributor: fullname: Liu – volume: 180 start-page: 79 year: 2002 end-page: 95 ident: bib42 article-title: Antioxidant nutrients and adriamycin toxicity publication-title: Toxicology contributor: fullname: Ramírez-Tortosa – volume: 60 start-page: 373 year: 2009 end-page: 381 ident: bib31 article-title: Angiotensin-converting enzyme inhibition and angiotensin AT(1)-receptor antagonism equally improve doxorubicin-induced cardiotoxicity and nephrotoxicity publication-title: Pharmacol. Res. contributor: fullname: Abdel-Rahim – volume: 6 start-page: e25878 year: 2011 ident: bib3 article-title: Strawberry polyphenols attenuate ethanol-induced gastric lesions in rats by activation of antioxidant enzymes and attenuation of MDA increase publication-title: PLoS One contributor: fullname: Battino – volume: 80 start-page: 1307 year: 2000 end-page: 1313 ident: bib11 article-title: Antioxidant properties of domesticated and wild Rubus species publication-title: J. Sci. Food Agric. contributor: fullname: Davies – volume: 20 start-page: 22 year: 2015 end-page: 33 ident: bib36 article-title: Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress publication-title: Mitochondrion contributor: fullname: Ascensão – volume: 280 start-page: 42026 year: 2005 end-page: 42035 ident: bib40 article-title: Rotenone model of Parkinson’s disease: multiple brain mitochondria dysfunctions after short-term systemic rotenone intoxication publication-title: J. Biol. Chem. contributor: fullname: Greenamyre – volume: 181 start-page: 375 year: 1991 end-page: 382 ident: bib30 article-title: Cytochrome oxidase induction after oxidative stress induced by Adriamycin in liver rat fed dietary olive oil publication-title: Biochem. Biophys. Res. Commun. contributor: fullname: Lenaz – volume: 259 start-page: 111 year: 2008 end-page: 118 ident: bib9 article-title: Curcumin down-regulates the multidrugresistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway publication-title: Cancer Lett. contributor: fullname: Lee – volume: 16 start-page: 1 year: 2015 end-page: 25 ident: bib18 article-title: AMPK as a new attractive therapeutic target for disease prevention: the role of dietary compounds publication-title: Curr. Drug Targets contributor: fullname: Battino – volume: 19 start-page: 7798 year: 2014 end-page: 7816 ident: bib20 article-title: Polyphenol-rich strawberry extract protects human dermal fibroblasts against hydrogen peroxide oxidative damage and improves mitochondrial functionality publication-title: Molecules contributor: fullname: Battino – volume: 82 start-page: 70 year: 1959 end-page: 77 ident: bib15 article-title: Tissue sulfahydryl groups publication-title: Arch. Biochem. Biophys. contributor: fullname: Ellman – volume: 6 start-page: e21746 year: 2011 ident: bib46 article-title: High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria publication-title: PlosOne contributor: fullname: Murphy – volume: 98 start-page: 1253 year: 1996 end-page: 1260 ident: bib55 article-title: The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice publication-title: J. Clin. Invest contributor: fullname: St Clair – volume: 123 start-page: 1939 year: 1993 end-page: 1951 ident: bib56 article-title: AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet publication-title: J. Nutr. contributor: fullname: Fahey – volume: 28 start-page: 49 year: 1997 end-page: 55 ident: bib50 article-title: Total Phenol analysis: automation and comparison with manual methods publication-title: Am. J. Enol. Viticult contributor: fullname: Singleton – volume: 62 start-page: 3935 year: 2014 end-page: 3943 ident: bib13 article-title: Doxorubicin-induced oxidative stress in rats is efficiently counteracted by dietary anthocyanin differently enriched strawberry (Fragaria × ananassa Duch.) publication-title: J. Agric. Food Chem. contributor: fullname: Battino – volume: 117 start-page: 171 year: 2003 end-page: 187 ident: bib29 article-title: Response of selected antioxidants and pigments in tissues of Rosa hybrida and Fuchsia hybrida to supplemental UV-A exposure publication-title: Physiol. Plant contributor: fullname: Schapendonk – volume: 48 start-page: 1425 year: 2010 end-page: 1438 ident: bib27 article-title: New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients publication-title: Food Chem. Toxicol. contributor: fullname: Ramirez-Tortosa – volume: 25 start-page: 289 year: 2014 end-page: 294 ident: bib2 article-title: One-month strawberry-rich anthocyanin supplementation ameliorates cardiovascular risk, oxidative stress markers and platelet activation in humans publication-title: J. Nutr. Biochem. contributor: fullname: Battino – volume: 56 start-page: 185 year: 2004 end-page: 229 ident: bib39 article-title: Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity publication-title: Pharmacol. Rev. contributor: fullname: Gianni – volume: 249 start-page: 7130 year: 1974 end-page: 7139 ident: bib28 article-title: Glutathione-S-transferase: the first enzymatic step in mercapturic acid formation publication-title: J. Biol. Chem. contributor: fullname: Jacoby – volume: 79 start-page: 92 year: 2015 end-page: 103 ident: bib17 article-title: α-Enolase plays a catalytically independent role in doxorubicin-induced cardiomyocyte apoptosis and mitochondrial dysfunction publication-title: J. Mol. Cell Cardiol. contributor: fullname: Liu – volume: 62 start-page: 3867 year: 2014 end-page: 3876 ident: bib19 article-title: Strawberry and human health: effects beyond antioxidant activity publication-title: J. Agric. Food Chem. contributor: fullname: Battino – volume: 34 start-page: 1294 year: 2007 end-page: 1299 ident: bib48 article-title: Chronic supplementation of creatine and vitamins C and E increases survival and improves biochemical parameters after doxorubicin treatment in rats publication-title: Clin. Exp. Pharmacol. Physiol. contributor: fullname: Costa Rosa – volume: 186 start-page: 464 year: 1990 end-page: 478 ident: bib34 article-title: Determination of carbonyl content in oxidatively modified proteins publication-title: Methods Enzymol. contributor: fullname: Stadtman – volume: 26 start-page: 1231 year: 1999 end-page: 1237 ident: bib45 article-title: Antioxidant activity applying an improved ABTS radical cation decolorization assay publication-title: Free Radic. Biol. Med. contributor: fullname: Rice-Evans – volume: 3 start-page: 169 year: 2013 end-page: 179 ident: bib47 article-title: Effects of an acute strawberry (Fragaria× ananassa) consumption on the plasma antioxidant status of healthy subjects publication-title: J. Berry Res. contributor: fullname: Alavarez-Suarez – volume: 14 start-page: 2274 year: 2011 end-page: 2284 ident: bib4 article-title: Mediterranean diet pyramid today. Science and cultural updates publication-title: Public Health Nutr. contributor: fullname: Serra-majem – volume: 21 start-page: 130 year: 1984 end-page: 132 ident: bib33 article-title: A modified spectrophotometric assay of superoxide dismutase publication-title: Indian J. Biochem. Biophys. contributor: fullname: Viswanathan – volume: 96 start-page: 1388 year: 2009 end-page: 1398 ident: bib8 article-title: Doxorubicin inactivates myocardial cytochrome c oxidase in rats: cardioprotection by Mito-Q publication-title: Biophys. J. contributor: fullname: Kalyanaraman – volume: 9 start-page: 331 year: 1999 end-page: 336 ident: bib43 article-title: Olive oil supplemented with vitamin E affects mitochondrial coenzyme Q levels in liver of rats after an oxidative stress induced by adriamycin publication-title: Biofactors contributor: fullname: Mataix – volume: 202 start-page: 384 year: 1992 end-page: 389 ident: bib32 article-title: Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein publication-title: Anal. Biochem. contributor: fullname: Wolff – volume: 156 start-page: 87 year: 2014 end-page: 93 ident: bib52 article-title: Strawberry intake increases blood fluid, erythrocyte and mononuclear cell defenses against oxidative challenge publication-title: Food Chem. contributor: fullname: Battino – volume: 0 start-page: 1 year: 2016 end-page: 14 ident: bib16 article-title: The healthy effects of strawberry polyphenols: which strategy behind antioxidant capacity? publication-title: Crit. Rev. Food Sci. Nutr. contributor: fullname: Battino – volume: 76 start-page: 178 year: 2006 end-page: 183 ident: bib38 article-title: Olive oil and mitochondrial oxidative stress publication-title: Int. J. Vitam. Nutr. Res. contributor: fullname: Quiles – volume: 2 start-page: 337 year: 2008 end-page: 345 ident: bib10 article-title: Schisandra fructus extract ameliorates doxorubicin-induce cytotoxicity in cardiomyocytes: altered gene expression for detoxification enzymes publication-title: Genes Nutr. contributor: fullname: Chun – volume: 28 start-page: 9 year: 2012 end-page: 19 ident: bib24 article-title: The strawberry: composition, nutritional quality, and impact on human health publication-title: Nutrition contributor: fullname: Battino – volume: 113 start-page: 484 year: 1985 end-page: 490 ident: bib7 article-title: Glutathione reductase publication-title: Methods Enzymol. contributor: fullname: Mannervik – volume: 40 start-page: 374 year: 2007 ident: 10.1016/j.fct.2016.06.003_bib35 article-title: Anthocyanin pigments in strawberry publication-title: LWT-Food Scien. Tech. doi: 10.1016/j.lwt.2005.09.018 contributor: fullname: Lopes da Silva – volume: 48 start-page: 1178 issue: 5 year: 2010 ident: 10.1016/j.fct.2016.06.003_bib14 article-title: Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats publication-title: Food Chem. Toxicol. doi: 10.1016/j.fct.2010.02.008 contributor: fullname: Elberry – volume: 3 start-page: 169 year: 2013 ident: 10.1016/j.fct.2016.06.003_bib47 article-title: Effects of an acute strawberry (Fragaria× ananassa) consumption on the plasma antioxidant status of healthy subjects publication-title: J. Berry Res. doi: 10.3233/JBR-130055 contributor: fullname: Romandini – volume: 14 start-page: 2274 year: 2011 ident: 10.1016/j.fct.2016.06.003_bib4 article-title: Mediterranean diet pyramid today. Science and cultural updates publication-title: Public Health Nutr. doi: 10.1017/S1368980011002515 contributor: fullname: Bach-Faig – volume: 56 start-page: 185 year: 2004 ident: 10.1016/j.fct.2016.06.003_bib39 article-title: Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity publication-title: Pharmacol. Rev. doi: 10.1124/pr.56.2.6 contributor: fullname: Minotti – volume: 62 start-page: 3935 issue: 18 year: 2014 ident: 10.1016/j.fct.2016.06.003_bib13 article-title: Doxorubicin-induced oxidative stress in rats is efficiently counteracted by dietary anthocyanin differently enriched strawberry (Fragaria × ananassa Duch.) publication-title: J. Agric. Food Chem. doi: 10.1021/jf405721d contributor: fullname: Diamanti – volume: 117 start-page: 171 year: 2003 ident: 10.1016/j.fct.2016.06.003_bib29 article-title: Response of selected antioxidants and pigments in tissues of Rosa hybrida and Fuchsia hybrida to supplemental UV-A exposure publication-title: Physiol. Plant doi: 10.1034/j.1399-3054.2003.00037.x contributor: fullname: Helsper – volume: 21 start-page: 130 year: 1984 ident: 10.1016/j.fct.2016.06.003_bib33 article-title: A modified spectrophotometric assay of superoxide dismutase publication-title: Indian J. Biochem. Biophys. contributor: fullname: Kakkar – volume: 9 start-page: 331 year: 1999 ident: 10.1016/j.fct.2016.06.003_bib43 article-title: Olive oil supplemented with vitamin E affects mitochondrial coenzyme Q levels in liver of rats after an oxidative stress induced by adriamycin publication-title: Biofactors doi: 10.1002/biof.5520090232 contributor: fullname: Quiles – volume: 25 start-page: 289 issue: 3 year: 2014 ident: 10.1016/j.fct.2016.06.003_bib2 article-title: One-month strawberry-rich anthocyanin supplementation ameliorates cardiovascular risk, oxidative stress markers and platelet activation in humans publication-title: J. Nutr. Biochem. doi: 10.1016/j.jnutbio.2013.11.002 contributor: fullname: Alvarez-Suarez – volume: 80 start-page: 1307 year: 2000 ident: 10.1016/j.fct.2016.06.003_bib11 article-title: Antioxidant properties of domesticated and wild Rubus species publication-title: J. Sci. Food Agric. doi: 10.1002/1097-0010(200007)80:9<1307::AID-JSFA638>3.0.CO;2-P contributor: fullname: Deighton – volume: 72 start-page: 248 year: 1976 ident: 10.1016/j.fct.2016.06.003_bib6 article-title: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding publication-title: Anal. Biochem. doi: 10.1016/0003-2697(76)90527-3 contributor: fullname: Bradford – volume: 98 start-page: 1253 year: 1996 ident: 10.1016/j.fct.2016.06.003_bib55 article-title: The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice publication-title: J. Clin. Invest doi: 10.1172/JCI118909 contributor: fullname: Yen – volume: 156 start-page: 87 year: 2014 ident: 10.1016/j.fct.2016.06.003_bib52 article-title: Strawberry intake increases blood fluid, erythrocyte and mononuclear cell defenses against oxidative challenge publication-title: Food Chem. doi: 10.1016/j.foodchem.2014.01.098 contributor: fullname: Tulipani – volume: 6 start-page: e25878 year: 2011 ident: 10.1016/j.fct.2016.06.003_bib3 article-title: Strawberry polyphenols attenuate ethanol-induced gastric lesions in rats by activation of antioxidant enzymes and attenuation of MDA increase publication-title: PLoS One doi: 10.1371/journal.pone.0025878 contributor: fullname: Alvarez-Suarez – volume: 180 start-page: 79 issue: 1 year: 2002 ident: 10.1016/j.fct.2016.06.003_bib42 article-title: Antioxidant nutrients and adriamycin toxicity publication-title: Toxicology doi: 10.1016/S0300-483X(02)00383-9 contributor: fullname: Quiles – volume: 202 start-page: 384 issue: 2 year: 1992 ident: 10.1016/j.fct.2016.06.003_bib32 article-title: Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein publication-title: Anal. Biochem. doi: 10.1016/0003-2697(92)90122-N contributor: fullname: Jiang – volume: 28 start-page: 9 year: 2012 ident: 10.1016/j.fct.2016.06.003_bib24 article-title: The strawberry: composition, nutritional quality, and impact on human health publication-title: Nutrition doi: 10.1016/j.nut.2011.08.009 contributor: fullname: Giampieri – volume: 113 start-page: 484 year: 1985 ident: 10.1016/j.fct.2016.06.003_bib7 article-title: Glutathione reductase publication-title: Methods Enzymol. doi: 10.1016/S0076-6879(85)13062-4 contributor: fullname: Carlberg – volume: 186 start-page: 464 year: 1990 ident: 10.1016/j.fct.2016.06.003_bib34 article-title: Determination of carbonyl content in oxidatively modified proteins publication-title: Methods Enzymol. doi: 10.1016/0076-6879(90)86141-H contributor: fullname: Levine – volume: 128 start-page: 180 year: 2011 ident: 10.1016/j.fct.2016.06.003_bib51 article-title: Strawberry consumption improves plasma antioxidant status and erythrocyte resistance to oxidative haemolysis in humans publication-title: Food Chem. doi: 10.1016/j.foodchem.2011.03.025 contributor: fullname: Tulipani – volume: 90 start-page: 25 issue: 1 year: 2014 ident: 10.1016/j.fct.2016.06.003_bib25 article-title: Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer publication-title: Biochem. Pharmacol. doi: 10.1016/j.bcp.2014.04.001 contributor: fullname: Granados-Principal – volume: 26 start-page: 1231 year: 1999 ident: 10.1016/j.fct.2016.06.003_bib45 article-title: Antioxidant activity applying an improved ABTS radical cation decolorization assay publication-title: Free Radic. Biol. Med. doi: 10.1016/S0891-5849(98)00315-3 contributor: fullname: Re – volume: 239 start-page: 70 year: 1996 ident: 10.1016/j.fct.2016.06.003_bib5 article-title: Ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: the FRAP assay publication-title: Anal. Biochem. doi: 10.1006/abio.1996.0292 contributor: fullname: Benzie – volume: 50 start-page: 3010 year: 2002 ident: 10.1016/j.fct.2016.06.003_bib12 article-title: Thermal processing enhances the nutritional values of tomatoes by increasing the total antioxidant activity publication-title: J. Agric. Food Chem. doi: 10.1021/jf0115589 contributor: fullname: Dewanto – volume: 19 start-page: 7798 year: 2014 ident: 10.1016/j.fct.2016.06.003_bib20 article-title: Polyphenol-rich strawberry extract protects human dermal fibroblasts against hydrogen peroxide oxidative damage and improves mitochondrial functionality publication-title: Molecules doi: 10.3390/molecules19067798 contributor: fullname: Giampieri – volume: 79 start-page: 92 year: 2015 ident: 10.1016/j.fct.2016.06.003_bib17 article-title: α-Enolase plays a catalytically independent role in doxorubicin-induced cardiomyocyte apoptosis and mitochondrial dysfunction publication-title: J. Mol. Cell Cardiol. doi: 10.1016/j.yjmcc.2014.11.007 contributor: fullname: Gao – volume: 96 start-page: 1388 year: 2009 ident: 10.1016/j.fct.2016.06.003_bib8 article-title: Doxorubicin inactivates myocardial cytochrome c oxidase in rats: cardioprotection by Mito-Q publication-title: Biophys. J. doi: 10.1016/j.bpj.2008.10.042 contributor: fullname: Chandran – volume: 60 start-page: 2322 year: 2012 ident: 10.1016/j.fct.2016.06.003_bib22 article-title: Photoprotective potential of strawberry (Fragaria× ananassa) extract against UV-A irradiation damage on human fibroblasts publication-title: J. Agric. Food Chem. doi: 10.1021/jf205065x contributor: fullname: Giampieri – volume: 76 start-page: 178 issue: 4 year: 2006 ident: 10.1016/j.fct.2016.06.003_bib38 article-title: Olive oil and mitochondrial oxidative stress publication-title: Int. J. Vitam. Nutr. Res. doi: 10.1024/0300-9831.76.4.178 contributor: fullname: Mataix – volume: 280 start-page: 42026 issue: 51 year: 2005 ident: 10.1016/j.fct.2016.06.003_bib40 article-title: Rotenone model of Parkinson’s disease: multiple brain mitochondria dysfunctions after short-term systemic rotenone intoxication publication-title: J. Biol. Chem. doi: 10.1074/jbc.M508628200 contributor: fullname: Panov – volume: 34 start-page: 1294 year: 2007 ident: 10.1016/j.fct.2016.06.003_bib48 article-title: Chronic supplementation of creatine and vitamins C and E increases survival and improves biochemical parameters after doxorubicin treatment in rats publication-title: Clin. Exp. Pharmacol. Physiol. doi: 10.1111/j.1440-1681.2007.04717.x contributor: fullname: Santos – volume: 39 start-page: 3002 issue: 10 year: 2007 ident: 10.1016/j.fct.2016.06.003_bib53 article-title: Protective effects of MnM2Py4P and Mn-salen against small bowel ischemia/reperfusion injury in rats using an in vivo and an ex vivo electron paramagnetic resonance technique with a spin probe publication-title: Transpl. Proc. doi: 10.1016/j.transproceed.2007.08.091 contributor: fullname: Watanabe – volume: 82 start-page: 70 year: 1959 ident: 10.1016/j.fct.2016.06.003_bib15 article-title: Tissue sulfahydryl groups publication-title: Arch. Biochem. Biophys. doi: 10.1016/0003-9861(59)90090-6 contributor: fullname: Ellman – volume: 20 start-page: 22 year: 2015 ident: 10.1016/j.fct.2016.06.003_bib36 article-title: Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress publication-title: Mitochondrion doi: 10.1016/j.mito.2014.10.008 contributor: fullname: Marques-Aleixo – volume: 16 start-page: 1 year: 2015 ident: 10.1016/j.fct.2016.06.003_bib18 article-title: AMPK as a new attractive therapeutic target for disease prevention: the role of dietary compounds publication-title: Curr. Drug Targets contributor: fullname: Gasparrini – volume: 6 start-page: e21746 issue: 7 year: 2011 ident: 10.1016/j.fct.2016.06.003_bib46 article-title: High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria publication-title: PlosOne doi: 10.1371/journal.pone.0021746 contributor: fullname: Rogers – volume: 2 start-page: 337 year: 2008 ident: 10.1016/j.fct.2016.06.003_bib10 article-title: Schisandra fructus extract ameliorates doxorubicin-induce cytotoxicity in cardiomyocytes: altered gene expression for detoxification enzymes publication-title: Genes Nutr. doi: 10.1007/s12263-007-0073-y contributor: fullname: Choi – volume: 5 start-page: 1939 year: 2014 ident: 10.1016/j.fct.2016.06.003_bib21 article-title: An anthocyanin-rich strawberry extract protects against oxidative stress damage and improves mitochondrial functionality in human dermal fibroblasts exposed to an oxidizing agent publication-title: Food Funct. doi: 10.1039/C4FO00048J contributor: fullname: Giampieri – volume: 0 start-page: 1 year: 2016 ident: 10.1016/j.fct.2016.06.003_bib16 article-title: The healthy effects of strawberry polyphenols: which strategy behind antioxidant capacity? publication-title: Crit. Rev. Food Sci. Nutr. contributor: fullname: Forbes-Hernandez – volume: 20 start-page: 411 year: 1978 ident: 10.1016/j.fct.2016.06.003_bib41 article-title: Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues publication-title: Methods Cell. Biol. doi: 10.1016/S0091-679X(08)62030-0 contributor: fullname: Pedersen – volume: 123 start-page: 1939 issue: 11 year: 1993 ident: 10.1016/j.fct.2016.06.003_bib56 article-title: AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet publication-title: J. Nutr. doi: 10.1093/jn/123.11.1939 contributor: fullname: Reeves – volume: 48 start-page: 1425 year: 2010 ident: 10.1016/j.fct.2016.06.003_bib27 article-title: New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients publication-title: Food Chem. Toxicol. doi: 10.1016/j.fct.2010.04.007 contributor: fullname: Granados-Principal – volume: 103 start-page: 287 year: 1979 ident: 10.1016/j.fct.2016.06.003_bib49 article-title: Increased biliary glutathione disulfide release in chronically ethanol treated rats publication-title: FEBS Lett. doi: 10.1016/0014-5793(79)81346-0 contributor: fullname: Sies – volume: 6 start-page: 1386 year: 2015 ident: 10.1016/j.fct.2016.06.003_bib23 article-title: Strawberry as a health promoter: an evidence based review publication-title: Food Funct. doi: 10.1039/C5FO00147A contributor: fullname: Giampieri – volume: 18 start-page: S129 year: 1997 ident: 10.1016/j.fct.2016.06.003_bib37 article-title: Coenzyme Q content depends upon oxidative stress and dietary fat unsaturation publication-title: Mol. Asp. Med. doi: 10.1016/S0098-2997(97)00019-8 contributor: fullname: Mataix – volume: 28 start-page: 49 year: 1997 ident: 10.1016/j.fct.2016.06.003_bib50 article-title: Total Phenol analysis: automation and comparison with manual methods publication-title: Am. J. Enol. Viticult doi: 10.5344/ajev.1977.28.1.49 contributor: fullname: Slinkard – volume: 105 start-page: 121 year: 1984 ident: 10.1016/j.fct.2016.06.003_bib1 article-title: Catalase in vitro publication-title: Methods Enzymol. doi: 10.1016/S0076-6879(84)05016-3 contributor: fullname: Aebi – volume: 259 start-page: 111 year: 2008 ident: 10.1016/j.fct.2016.06.003_bib9 article-title: Curcumin down-regulates the multidrugresistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway publication-title: Cancer Lett. doi: 10.1016/j.canlet.2007.10.003 contributor: fullname: Choi – volume: 181 start-page: 375 year: 1991 ident: 10.1016/j.fct.2016.06.003_bib30 article-title: Cytochrome oxidase induction after oxidative stress induced by Adriamycin in liver rat fed dietary olive oil publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/S0006-291X(05)81429-9 contributor: fullname: Huertas – volume: 60 start-page: 373 issue: 5 year: 2009 ident: 10.1016/j.fct.2016.06.003_bib31 article-title: Angiotensin-converting enzyme inhibition and angiotensin AT(1)-receptor antagonism equally improve doxorubicin-induced cardiotoxicity and nephrotoxicity publication-title: Pharmacol. Res. doi: 10.1016/j.phrs.2009.05.007 contributor: fullname: Ibrahim – volume: 249 start-page: 7130 year: 1974 ident: 10.1016/j.fct.2016.06.003_bib28 article-title: Glutathione-S-transferase: the first enzymatic step in mercapturic acid formation publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(19)42083-8 contributor: fullname: Habig – volume: 250 start-page: 66 year: 1997 ident: 10.1016/j.fct.2016.06.003_bib57 article-title: Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress publication-title: Anal. Biochem. doi: 10.1006/abio.1997.2187 contributor: fullname: Yamashita – volume: 62 start-page: 3867 year: 2014 ident: 10.1016/j.fct.2016.06.003_bib19 article-title: Strawberry and human health: effects beyond antioxidant activity publication-title: J. Agric. Food Chem. doi: 10.1021/jf405455n contributor: fullname: Giampieri – volume: 31 start-page: 129 year: 1999 ident: 10.1016/j.fct.2016.06.003_bib44 article-title: Vitamin E supplementation increases the stability and the in vivo antioxidant capacity of refined olive oil publication-title: Free Radic. Res. doi: 10.1080/10715769900301421 contributor: fullname: Quiles – volume: 55 start-page: S117 year: 2011 ident: 10.1016/j.fct.2016.06.003_bib26 article-title: Hydroxytyrosol inhibits growth and cell proliferation and promotes high expression of sfrp4 in rat mammary tumours publication-title: Mol. Nutr. Food Res. doi: 10.1002/mnfr.201000220 contributor: fullname: Granados-Principal – volume: 41 start-page: 46 year: 2006 ident: 10.1016/j.fct.2016.06.003_bib54 article-title: Attenuation of doxorubicin induced contractile and mitochondrial dysfunction in mouse heart by cellular glutathione peroxidase publication-title: Free Radic. Biol. Med. doi: 10.1016/j.freeradbiomed.2006.02.024 contributor: fullname: Xiong |
SSID | ssj0007176 |
Score | 2.4224877 |
Snippet | Doxorubicin (Dox), one of the most used chemotherapeutic agents, is known to generate oxidative stress and block DNA synthesis, which result in severe... |
SourceID | proquest crossref pubmed elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 128 |
SubjectTerms | Animals Antibiotics, Antineoplastic - toxicity Antioxidants - metabolism Bioactive compounds Biomarkers - blood Body Weight Doxorubicin Doxorubicin - toxicity Fragaria Liver - drug effects Liver - pathology Male Mitochondrial functionality Organ Size Oxidative Stress Rats Rats, Wistar Strawberry |
Title | Strawberry consumption alleviates doxorubicin-induced toxicity by suppressing oxidative stress |
URI | https://dx.doi.org/10.1016/j.fct.2016.06.003 https://www.ncbi.nlm.nih.gov/pubmed/27286747 https://search.proquest.com/docview/1808697152 |
Volume | 94 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Na9swFH90yaGDUrbuK21XVNhpoCWOFFs-ltCSbayXtdDThL480oMdEqdtLv3b-yRZgTK2w26WsLB5T_693_P7EMAntJDOVLqiCISC8kpxWlZVSY0ZM4Q_I0ruC5x_XOaza_7tZnKzA9NUC-PTKjvsj5ge0LqbGXbSHC7m8-FPHzPLS7RYOW5S4Wup-2iOOO9B_-zr99nlFpDRYwkhS7yf-gUpuBnSvCrjMyqzPHTxTEdn_Wme_kY_gxm6eAX7HX8kZ_EVX8OOqw9gd5qObcPrVGq8OoC9-FOOxFqjN_DL96K912653BATai8DYBB_nsrd3LNOYpuHZrnWPt5O0V1HxVvSNg84bjdEb8hqvYips_VvgtM29A0nseLkLVxfnF9NZ7Q7YIEaJvKWMjvKy0KNubaMOeQmRrvMoclG1jQymbIF574_HdMTq9WIKY1fvzIiK2zGDOPsHfTqpnYfgIisMihohQpQXLmRshNtczHxjcyRAagBfE5ylYvYR0OmBLNbiUqQXgkyJNmxAfAkeflsM0jE-X8tO01akih0H_lQtWvWK5kJ9NzKArnKAN5H9W3fYlyMRY5O1eH_PfQIXvpRzAk8hl67XLuPyFNafQIvvjxmJ91ufALH7uee |
link.rule.ids | 315,786,790,4521,24144,27957,27958,45620,45714 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LaxsxEB6Cc0ihlDZ9uU8VeioIW5Z2V3sMpsFpEl-aQE4Vem1xDrvGXrfxv-9IWgVKaQ-97UusmNF-883OQwAf0UJ625iGIhBKKhotaN00NbV2xhH-rKxFKHC-XJaLa_Hlprg5gHmuhQlplQP2J0yPaD1cmQzSnKxXq8nXEDMra7RYJS5SGWqpD0VRMTGCw5Oz88XyHpDRY4khS3yehgE5uBnTvBobMipZGbt45q2z_jRPf6Of0QydPoZHA38kJ2mKT-DAt8dwNM_btuFxLjXeHsPD9FOOpFqjp_At9KL9afxmsyc21l5GwCBhP5Ufq8A6ievuus3OhHg7RXcdFe9I393heb8nZk-2u3VKnW2_E7zsYt9wkipOnsH16eer-YIOGyxQy2XZU-6mZV3pmTCOc4_cxBrPPJpsZE1Ty7SrhAj96bgpnNFTrg1-_dpKVjnGLRf8OYzarvUvgUjWWBS0Fkxoof1Uu8K4UhahkTkyAD2GT1muap36aKicYHarUAkqKEHFJDs-BpElr35bDApx_l_DPmQtKRR6iHzo1ne7rWISPbe6Qq4yhhdJffezmFUzWaJT9er_XvoejhZXlxfq4mx5_hoehDspP_ANjPrNzr9FztKbd8Oa_AVeeemQ |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Strawberry+consumption+alleviates+doxorubicin-induced+toxicity+by+suppressing+oxidative+stress&rft.jtitle=Food+and+chemical+toxicology&rft.au=Giampieri%2C+Francesca&rft.au=Alvarez-Suarez%2C+Jose+M.&rft.au=Gasparrini%2C+Massimiliano&rft.au=Forbes-+Hernandez%2C+Tamara+Y.&rft.date=2016-08-01&rft.issn=0278-6915&rft.volume=94&rft.spage=128&rft.epage=137&rft_id=info:doi/10.1016%2Fj.fct.2016.06.003&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_fct_2016_06_003 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0278-6915&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0278-6915&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0278-6915&client=summon |