Risk assessment of the cumulative acute exposure of Hungarian population to organophosphorus pesticide residues with regard to consumers of plant based foods

• Published in: Food and chemical toxicology Vol. 89; pp. 67 - 72
• Main Authors: Zentai, Andrea, Szabó, István J., Kerekes, Kata, Ambrus, Árpád
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.03.2016
• Subjects: Cumulative acute exposure; Diet; Effect of LOQ and zero residues; Environmental Exposure; Food Contamination; Humans; Hungary; Organophosphorus Compounds - analysis; Organophosphorus Compounds - toxicity; Organophosphorus pesticides; Pesticide Residues - analysis; Pesticide Residues - toxicity; Plants - chemistry; Probabilistic method; Risk Assessment; OP; Cumulative acute exposure; Effect of LOQ and zero residues; Probabilistic method; MRL; NOAEL; RPF; Organophosphorus pesticides; LOR; EFSA; LOQ
• ISSN: 0278-6915; 1873-6351
• DOI: 10.1016/j.fct.2016.01.016

Based on the Hungarian pesticide residues monitoring data of the last five years and the consumption data collected within a 3-day dietary record survey in 2009 (more than 2 million pesticide residue results and almost 5000, 0-101-year-old consumers 3 non-consecutive-day personal fruit and vegetable consumption data), the cumulative acute exposure of organophosphorus pesticide residues was evaluated. The relative potency factor approach was applied, with acephate chosen as index compound. According to our conservative calculation method, applying the measured residues only, the 99.95% of the 99th percentiles of calculated daily intakes was at or below 87 μg/kgbwday, indicating that the cumulative acute exposure of the whole Hungarian population (including all age classes) to organophosphorus compounds was not a health concern. •Inclusion of LOQ and zero values does not affect acute exposure of OP pesticides.•Cumulative exposure to OP is not a health concern in Hungary.•Exposure of 3–9 years age group is the highest.