A label-free fluorescent molecular beacon based on DNA-templated silver nanoclusters for detection of adenosine and adenosine deaminase

A simple and reliable fluorescent molecular beacon is developed utilizing DNA-templated silver nanoclusters as a signal indicator and adenosine triphosphate (ATP) and adenosine deaminase as mechanical activators.

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 48; no. 44; pp. 5488 - 5490
Main Authors Zhang, Min, Guo, Su-Miao, Li, Ying-Ru, Zuo, Peng, Ye, Bang-Ce
Format Journal Article
LanguageEnglish
Published England 01.01.2012
Subjects
Adenosine Deaminase - analysis
Adenosine Deaminase - chemistry
Adenosine Triphosphate - analysis
Adenosine Triphosphate - chemistry
Aptamers, Nucleotide - chemistry
ATP
Fluorescent Dyes
Metal Nanoparticles - chemistry
Sensitivity and Specificity
Silver - chemistry
Spectrometry, Fluorescence
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Summary:A simple and reliable fluorescent molecular beacon is developed utilizing DNA-templated silver nanoclusters as a signal indicator and adenosine triphosphate (ATP) and adenosine deaminase as mechanical activators.
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ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc31626a