Photoelectron dynamics in x-ray free-electron-laser diffractive imaging of biological samples

X-ray free electron lasers hold the promise of enabling atomic-resolution diffractive imaging of single biological molecules. We develop a hybrid continuum-particle model to describe the x-ray induced damage and find that the photoelectron dynamics and electrostatic confinement strongly affect the t...

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Bibliographic Details
Published inPhysical review letters Vol. 108; no. 23; p. 238101
Main Author Hau-Riege, Stefan P
Format Journal Article
LanguageEnglish
Published United States 08.06.2012
Subjects
Electrons
Image Processing, Computer-Assisted
Lasers
Membranes - chemistry
Membranes - radiation effects
Models, Theoretical
Scattering, Radiation
Thermodynamics
X-Rays
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Summary:X-ray free electron lasers hold the promise of enabling atomic-resolution diffractive imaging of single biological molecules. We develop a hybrid continuum-particle model to describe the x-ray induced damage and find that the photoelectron dynamics and electrostatic confinement strongly affect the time scale of the damage processes. These phenomena are not fully captured in hydrodynamic modeling approaches.
ISSN:1079-7114
DOI:10.1103/PhysRevLett.108.238101