Integration of HIV Testing in a Community Intervention for Tuberculosis Screening Among Household Contacts of Patients with Tuberculosis in Cameroon and Uganda

• Published in: Journal of acquired immune deficiency syndromes (1999) Vol. 95; no. 5; p. 431
• Main Authors: Tchakounte Youngui, Boris, Atwine, Daniel, Otai, David, Vasiliu, Anca, Ssekyanzi, Bob, Sih, Colette, Kana, Rogacien, Arinaitwe, Rinah, Cuer, Benjamin, Simo, Leonie, Okello, Richard, Tchendjou, Patrice, Casenghi, Martina, Kuate, Albert Kuate, Turyahabwe, Stavia, Cohn, Jennifer, Bonnet, Maryline, Tchounga, Boris Kevin
• Format: Journal Article
• Language: English
• Published: United States 15.04.2024
• Subjects: Adult; Cameroon - epidemiology; Child; Contact Tracing - methods; HIV Infections - complications; HIV Infections - diagnosis; HIV Infections - epidemiology; HIV Testing; Humans; Mass Screening - methods; Tuberculosis - diagnosis; Tuberculosis - epidemiology; Tuberculosis - prevention & control; Uganda - epidemiology; Uganda; Cameroon
• ISSN: 1944-7884
• DOI: 10.1097/QAI.0000000000003379

People living with HIV are considered at higher risk of developing severe forms of tuberculosis (TB) disease. Providing HIV testing to TB-exposed people is therefore critical. We present the results of integrating HIV testing into a community-based intervention for household TB contact management in Cameroon and Uganda. Trained community health workers visited the households of index patients with TB identified in 3 urban/semiurban and 6 rural districts or subdistricts as part of a cluster-randomized trial and provided TB screening to all household contacts. Voluntary HIV counseling and testing were offered to contacts aged 5 years or older with unknown HIV status. We describe the cascade of care for HIV testing and the factors associated with the acceptance of HIV testing. Overall, 1983 household contacts aged 5 years or older were screened for TB. Of these contacts, 1652 (83.3%) did not know their HIV status, 1457 (88.2%) accepted HIV testing, and 1439 (98.8%) received testing. HIV testing acceptance was lower among adults than children [adjusted odds ratio (aOR) = 0.35, 95% confidence interval (CI): 0.22 to 0.55], those living in household of an HIV-positive vs HIV-negative index case (aOR = 0.56, 95% CI: 0.38 to 0.83), and contacts requiring a reassessment visit after the initial TB screening visit vs asymptomatic contacts (aOR = 0.20, 95% CI: 0.06 to 0.67) and was higher if living in Uganda vs Cameroon (aOR = 4.54, 95% CI: 1.17 to 17.62) or if another contact of the same index case was tested for HIV (aOR = 9.22, 95% CI: 5.25 to 16.18). HIV testing can be integrated into community-based household TB contact screening and is well-accepted.