Cutaneous leukocytoclastic vasculitis associated with active Wegener's granulomatosis

• Published in: Journal of the American Academy of Dermatology Vol. 26; no. 4; pp. 579 - 584
• Main Authors: Mangold, Melissa C., Callen, Jeffrey P.
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.04.1992; Elsevier
• Subjects: Adult; Biological and medical sciences; Female; Granulomatosis with Polyangiitis - complications; Granulomatosis with Polyangiitis - immunology; Humans; Male; Medical sciences; Middle Aged; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Vasculitis, Leukocytoclastic, Cutaneous - etiology; Vasculitis, Leukocytoclastic, Cutaneous - immunology; Case study; Human; Pathology; Skin disease; Vasculitis; Systemic disease; Vascular disorders of the skin; Clinical form; Exploration; Wegener granulomatosis
• ISSN: 0190-9622; 1097-6787
• DOI: 10.1016/0190-9622(92)70084-S

Background: Cutaneous manifestations are common in Wegener's granulomatosis and may occur at any time during the illness. Objective: Our purpose was to describe the relation of the appearance of cutaneous leukocytoclastic vasculitis to activity and other manifestations of Wegener's granulomatosis. Methods: Three patients with Wegener's granulomatosis who had recent onset of skin lesions are reported. Data regarding the relation of their cutaneous disease to their systemic disease was collected. Results and conclusion: In each case, onset of the skin lesions of biopsy-proven cutaneous leukocytoclastic vasculitis was associated with activation of the systemic features of Wegener's granulomatosis.