Non-spherical polymersomes driven by directional aromatic interactions

Polymersomes, nanoscopic polymer vesicles self-as- sembled from synthetic block copolymers, are ideal can- didates for drug delivery and synthetic biology, due to their characteristic of high stability, chemical versatility and surface modifiability. Besides the dimensions, re- searchers have demons...

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Published inScience China materials Vol. 61; no. 3; pp. 437 - 438
Main Authors Luo, Mingyan, Luo, Yunjun, Li, Xiaoyu
Format Journal Article
LanguageEnglish
Published Beijing Science China Press 01.03.2018
Springer Nature B.V
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Summary:Polymersomes, nanoscopic polymer vesicles self-as- sembled from synthetic block copolymers, are ideal can- didates for drug delivery and synthetic biology, due to their characteristic of high stability, chemical versatility and surface modifiability. Besides the dimensions, re- searchers have demonstrated that the shape of polymer- somes also plays a crucial role in their performance [1]. However, the formation of polymersomes is largely dri- ven by the hydrophobic effect [2], which is non-direc- tional, and thus the resultant polymersomes are mostly spherical. Anisotropic polymersomes or vesicular micelles have been reported by van Hest.
Bibliography:Polymersomes, nanoscopic polymer vesicles self-as- sembled from synthetic block copolymers, are ideal can- didates for drug delivery and synthetic biology, due to their characteristic of high stability, chemical versatility and surface modifiability. Besides the dimensions, re- searchers have demonstrated that the shape of polymer- somes also plays a crucial role in their performance [1]. However, the formation of polymersomes is largely dri- ven by the hydrophobic effect [2], which is non-direc- tional, and thus the resultant polymersomes are mostly spherical. Anisotropic polymersomes or vesicular micelles have been reported by van Hest.
10-1236/TB
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ISSN:2095-8226
2199-4501
DOI:10.1007/s40843-017-9181-2