QUADRONE, A NEW ANTITUMOR SUBSTANCE PRODUCED BY ASPERGILLUS TERREUS PRODUCTION, ISOLATION AND PROPERTIES

A new antitumor compound named quadrone was isolated from the culture broth of Aspergillus terreus NRRL 11, 156. Quadrone was active against KB cells in vitro, but did not possess antimicrobial activity.

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Bibliographic Details
Published inJournal of antibiotics Vol. 31; no. 1; pp. 38 - 42
Main Authors CALTON, G. J., RANIERI, R. L., ESPENSHADE, M. A.
Format Journal Article
LanguageEnglish
Published Japan JAPAN ANTIBIOTICS RESEARCH ASSOCIATION 1978
Subjects
Antibiotics, Antineoplastic - isolation & purification
Antibiotics, Antineoplastic - pharmacology
Aspergillus - metabolism
Cells, Cultured
Chemical Phenomena
Chemistry
Fermentation
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Summary:A new antitumor compound named quadrone was isolated from the culture broth of Aspergillus terreus NRRL 11, 156. Quadrone was active against KB cells in vitro, but did not possess antimicrobial activity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.31.38