Diffusion Tensor Imaging in Radiation-Induced Myelopathy

Radiation myelopathy (RM) is a rare complication of spinal cord irradiation. Diagnosis is based on the history of radiotherapy, laboratory tests, and magnetic resonance imaging of the spinal cord. The MRI findings may nevertheless be quite unspecific. In this paper, we describe the findings of diffu...

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Bibliographic Details
Published inJournal of neuroimaging Vol. 25; no. 5; p. 836
Main Authors Keřkovský, Miloš, Zitterbartová, Jana, Pour, Luděk, Šprláková-Puková, Andrea, Mechl, Marek
Format Journal Article
LanguageEnglish
Published United States 01.09.2015
Subjects
Diagnosis, Differential
Diffusion Tensor Imaging - methods
Humans
Male
Middle Aged
Radiation Injuries - etiology
Radiation Injuries - pathology
Radiotherapy, Conformal - adverse effects
Spinal Cord Diseases - etiology
Spinal Cord Diseases - pathology
Spinal Neoplasms - radiotherapy
Treatment Outcome
diffusion tensor imaging
magnetic resonance imaging
Radiation myelopathy
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Summary:Radiation myelopathy (RM) is a rare complication of spinal cord irradiation. Diagnosis is based on the history of radiotherapy, laboratory tests, and magnetic resonance imaging of the spinal cord. The MRI findings may nevertheless be quite unspecific. In this paper, we describe the findings of diffusion tensor imaging in a case of the delayed form of RM. We observed areas of restricted diffusion within the spinal cord which probably corresponded to the ischemic changes. This would concur with the currently accepted pathogenetic theory concerning RM.
ISSN:1552-6569
DOI:10.1111/jon.12187