Urinary surge of human luteinizing hormone in infertile women

• Published in: International journal of gynecology and obstetrics Vol. 32; no. 2; pp. 145 - 152
• Main Authors: Okamura, T., Kigasawa, K., Takeuchi, T., Nishii, O., Yaginuma, T.
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 01.06.1990; Elsevier Science
• Subjects: Adult; Biological and medical sciences; Birth control; Estradiol - urine; Female; Gonadotropin-Releasing Hormone - pharmacology; Gynecology. Andrology. Obstetrics; Humans; Immunoassay - methods; Infertility, Female - drug therapy; Infertility, Female - metabolism; Luteinizing Hormone - urine; Luteinizing hormone in urine; Measurement of urinary LH; Medical sciences; Menstrual Cycle - physiology; Pituitary Gland - metabolism; Pregnanediol - urine; Sterility. Assisted procreation; Surge of urinary LH; Measurement of urinary LH; Surge of urinary LH; Luteinizing hormone in urine; Human; Urine; Adenohypophyseal hormone; Pathophysiology; Female sterility; Peak; Diagnosis; Hormonal investigation; Gonadotropin; Glycoprotein hormone; LH; Immunological method
• ISSN: 0020-7292; 1879-3479
• DOI: 10.1016/0020-7292(90)90480-9

An improved semiquantitative immunoassay method allows human luteinizing hormone (hLH) in urine to be detected from 2.5 to 640 mIU/ml has developed. With this method, the hLH surges in every 3 h urine samples while awake were measured in 8 normal and 12 infertile women. The result was that the urinary hLH surge in infertility was insufficient regardless of the high urinary E 2 value. This result may play, at least in part, an etiologic role in infertility.