Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion

Summary Tranexamic acid is an anti‐fibrinolytic agent frequently used in pediatric surgery. Common side effects include nausea, flushing, and headache, but in rare instances, it may produce anaphylaxis; with only one previously reported case in a 72‐year‐old man. We report a case of a delayed anaphy...

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Bibliographic Details
Published inPediatric anesthesia Vol. 27; no. 7; pp. 774 - 775
Main Authors Chiem, Jennifer, Ivanova, Iskra, Parker, Andrew, Krengel, Walter, Jimenez, Nathalia, Polaner, David
Format Journal Article
LanguageEnglish
Published France Wiley Subscription Services, Inc 01.07.2017
Subjects
Adolescent
anaphylaxis
Anaphylaxis - etiology
Anaphylaxis - therapy
Anesthesia, General
Anesthesia, Intravenous
Antifibrinolytic agents
Antifibrinolytic Agents - adverse effects
Blood Loss, Surgical
Blood Transfusion
Humans
Hypersensitivity, Delayed - therapy
Intraoperative Complications - therapy
Male
Monitoring, Intraoperative
Pediatrics
scoliosis
Skin Tests
Spinal Fusion
tranexamic acid
Tranexamic Acid - adverse effects
antifibrinolytic agents
anaphylaxis
spinal fusion
pediatrics
scoliosis
tranexamic acid
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Summary:Summary Tranexamic acid is an anti‐fibrinolytic agent frequently used in pediatric surgery. Common side effects include nausea, flushing, and headache, but in rare instances, it may produce anaphylaxis; with only one previously reported case in a 72‐year‐old man. We report a case of a delayed anaphylactic reaction in a pediatric patient undergoing posterior spine fusion; and discuss the intraoperative management of the acute event, immunologic confirmation, and subsequent anesthetic approach.
ISSN:1155-5645
1460-9592
DOI:10.1111/pan.13141