Bioresorbable composite polymeric materials for tissue engineering applications

This review covers the development of bioresorbable polymeric composites for applications in tissue engineering. Various commercially available bioresobable polymers are described, with emphasis on recent bioresorbable composites based on natural and synthetic polymers. Bioresorbable polymers contai...

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Published inInternational journal of polymeric materials Vol. 70; no. 13; pp. 926 - 940
Main Authors Hajebi, Sakineh, Mohammadi Nasr, SAeed, Rabiee, Navid, Bagherzadeh, Mojtaba, Ahmadi, Sepideh, Rabiee, Mohammad, Tahriri, Mohammadreza, Tayebi, Lobat, Hamblin, Michael R.
Format Journal Article
LanguageEnglish
Published Philadelphia Taylor & Francis 02.09.2021
Taylor & Francis Ltd
Subjects
Biocompatibility
Biodegradable polymer
Biomedical materials
bioresorbable
composite
Composite materials
Degradation
Hydrogels
Hydrolysis
Hydroxy acids
Polyanhydrides
Polyethylene glycol
Polymers
Polyurethane resins
Tissue engineering
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Summary:This review covers the development of bioresorbable polymeric composites for applications in tissue engineering. Various commercially available bioresobable polymers are described, with emphasis on recent bioresorbable composites based on natural and synthetic polymers. Bioresorbable polymers contain hydrolyzable bonds, which are subjected to chemical degradation via either reactive hydrolysis or enzyme-catalyzed active hydrolysis. For synthetic polymers, chemical hydrolysis is the most important mode of degradation. The degradation rate can be controlled by varying the molecular weight and crystallinity. Examples of bioresorbable polymers are: polyurethane, poly(D,L)lactide, poly(lactic-co-glycolic) acid, poly(α-hydroxy acids), cross-linked polyester hydrogels, poly(orthoesters), polyanhydrides and polyethylene glycol.
ISSN:0091-4037
1563-535X
DOI:10.1080/00914037.2020.1765365