Reflectance Diffuse Optical Tomography: Its Application to Human Brain Mapping

We report the successful application of reflectance diffuse optical tomography (DOT) using near-infrared light with the new reconstruction algorithm that we developed to the observation of regional hemodynamic changes in the brain under specific mental tasks. Our results reveal the heterogeneous dis...

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Bibliographic Details
Published inJapanese Journal of Applied Physics Vol. 44; no. 9L; p. L1203
Main Authors Ueda, Yukio, Yamanaka, Takeshi, Yamashita, Daisuke, Suzuki, Toshihiko, Ohmae, Etsuko, Oda, Motoki, Yamashita, Yutaka
Format Journal Article
LanguageEnglish
Published 01.01.2005
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Summary:We report the successful application of reflectance diffuse optical tomography (DOT) using near-infrared light with the new reconstruction algorithm that we developed to the observation of regional hemodynamic changes in the brain under specific mental tasks. Our results reveal the heterogeneous distribution of oxyhemoglobin and deoxyhemoglobin in the brain, showing complementary images of oxyhemoglobin and deoxyhemoglobin changes in certain regions. We conclude that our reflectance DOT has practical potential for human brain mapping, as well as in the diagnostic imaging of brain diseases.
ISSN:0021-4922
1347-4065
DOI:10.1143/JJAP.44.L1203