Effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers

• Published in: Revista da Sociedade Brasileira de Medicina Tropical Vol. 47; no. 3; pp. 389 - 391
• Main Authors: Gauch, Lurdete Maria Rocha, Silveira-Gomes, Fabíola, Esteves, Renata Antunes, Pedrosa, Simone Soares, Gurgel, Ely Simone Cajueiro, Arruda, Alberto Cardoso, Marques-da-Silva, Silvia Helena
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Sociedade Brasileira de Medicina Tropical - SBMT 01.05.2014; Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: Aged; Antifungal Agents - isolation & purification; Antifungal Agents - pharmacology; Candida albicans; Candida albicans - drug effects; Candida albicans - isolation & purification; Dentures - microbiology; Female; Germ Tube; Humans; Male; Middle Aged; Oils, Volatile - pharmacology; Rosmarinus - chemistry; Rosmarinus officinalis; TROPICAL MEDICINE; Candida albicans; Germ Tube; Rosmarinus officinalis
• ISSN: 0037-8682; 1678-9849; 1678-9849
• DOI: 10.1590/0037-8682-0137-2013

The aim of this study was to investigate the effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or without 4% R. officinalis essential oil. The essential oil from R. officinalis completely inhibited germ tube formation in the investigated C. albicans isolates. The results demonstrate that the essential oil of R. officinalis modulates C. albicans pathogenicity through its primary virulence factor (i.e., germ tube formation was suppressed).