Acaricidal properties of the essential oil and precocene II obtained from Calea serrata (Asteraceae) on the cattle tick Rhipicephalus ( Boophilus) microplus (Acari: Ixodidae)

• Published in: Veterinary parasitology Vol. 179; no. 1; pp. 195 - 198
• Main Authors: Ribeiro, Vera Lucia Sardá, dos Santos, Jaqueline Campiol, Martins, João Ricardo, Schripsema, Jan, Siqueira, Ionara R., von Poser, Gilsane L., Apel, Miriam A.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 30.06.2011
• Subjects: acaricidal properties; Acaricide; Acaricides - chemistry; Acaricides - pharmacology; Animals; Asteraceae; Asteraceae - chemistry; Benzopyrans - chemistry; Benzopyrans - pharmacology; Boophilus; Calea serrata; chemical composition; Dose-Response Relationship, Drug; Essential oil; essential oils; indigenous species; insecticidal properties; Larva - drug effects; larvae; liver; Oils, Volatile - chemistry; Oils, Volatile - pharmacology; plant extracts; Plant Leaves - chemistry; Plant Oils - chemistry; Plant Oils - pharmacology; Plant Stems - chemistry; Precocene II; precocenes; Rhipicephalus; Rhipicephalus ( Boophilus) microplus; Rhipicephalus - drug effects; ticks; traditional medicine; Acaricide; Calea serrata; Essential oil; Rhipicephalus ( Boophilus) microplus; Precocene II
• ISSN: 0304-4017; 1873-2550
• DOI: 10.1016/j.vetpar.2011.02.006

Calea serrata Less. (Asteraceae), an endemic species of south Brazil known as “quebra-tudo”, is used in Afro-Brazilian religious rituals and in folk medicine for treating liver disorders. Phytochemical studies of the n-hexane extract of this plant demonstrated the presence of precocene II, a benzopyran derivative known for its insecticidal activity. The aim of this work was to isolate this benzopyran and determine the chemical composition of the essential oil of C. serrata and further to evaluate the acaricidal activity of the essential oil and precocene II against the larvae of Rhipicephalus ( Boophilus) microplus. The LC 99.9 and LC 50 values obtained with the oil, which presents precocene II and sesquiterpenes, were 3.94 μL/mL and 0.28 μL/mL, respectively. For precocene II this values were 4.25 mg/mL and 1.78 mg/mL, respectively. The results indicate a synergistic interaction between the components of the oil and precocene II.