The synthesis of a fungal isonitrile antibiotic via a novel radical addition-elimination reaction

The reaction of beta -stannyl acrylates with carbon radicals, generated from the corresponding bromides, to afford beta -alkyl acrylates is the key carbon-carbon coupling step in a synthesis of the fungal dienyl isonitrile antibiotic.

Saved in:
Bibliographic Details
Published inJournal of the Chemical Society. Chemical communications no. 2; pp. 133 - 134
Main Authors BALDWIN, J. E, KELLY, D. R, ZIEGLER, C. B
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 1984
Subjects
Alicyclic compounds
Alicyclic compounds, terpenoids, prostaglandins, steroids
Chemistry
Exact sciences and technology
Organic chemistry
Preparations and properties
Trichoderma
Antibiotic
Carboxylic acid
Isomerization
Dienic compound
Isocyanide
Monocyclic compound
Chemical coupling
Online AccessGet full text

Cover

More Information
Summary:The reaction of beta -stannyl acrylates with carbon radicals, generated from the corresponding bromides, to afford beta -alkyl acrylates is the key carbon-carbon coupling step in a synthesis of the fungal dienyl isonitrile antibiotic.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0022-4936
DOI:10.1039/c39840000133