ModeRNA server: an online tool for modeling RNA 3D structures

• Published in: Bioinformatics (Oxford, England) Vol. 27; no. 17; pp. 2441 - 2442
• Main Authors: ROTHER, Magdalena, MILANOWSKAL, Kaja, PUTON, Tomasz, JELENIEWICZ, Jaroslaw, ROTHER, Kristian, BUJNICKI, Janusz M
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.09.2011
• Subjects: Biological and medical sciences; Fundamental and applied biological sciences. Psychology; General aspects; Internet; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects); Models, Molecular; Nucleic Acid Conformation; RNA - chemistry; RNA, Untranslated - chemistry; Sequence Alignment; Sequence Analysis, RNA; Software; RNA; Structure; Modeling
• ISSN: 1367-4803; 1367-4811
• DOI: 10.1093/bioinformatics/btr400

The diverse functional roles of non-coding RNA molecules are determined by their underlying structure. ModeRNA server is an online tool for RNA 3D structure modeling by the comparative approach, based on a template RNA structure and a user-defined target-template sequence alignment. It offers an option to search for potential templates, given the target sequence. The server also provides tools for analyzing, editing and formatting of RNA structure files. It facilitates the use of the ModeRNA software and offers new options in comparison to the standalone program. ModeRNA server was implemented using the Python language and the Django web framework. It is freely available at http://iimcb.genesilico.pl/modernaserver. iamb@genesilico.pl.