Distance to highway and factory density related to lung cancer death and associated spatial heterogeneity in effects in Jiading District, Shanghai

• Published in: Environmental science and pollution research international Vol. 28; no. 45; pp. 64536 - 64551
• Main Authors: Zhang, Na, Wang, Yingjian, Yu, Hongjie, Zhang, Yiying, Xiang, Fang, Jiang, Honglin, Zheng, Yingyan, Xiong, Ying, Wang, Zhengzhong, Chen, Yue, Jiang, Qingwu, Shao, Yueqin, Zhou, Yibiao
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2021; Springer Nature B.V
• Subjects: Aquatic Pollution; Atmospheric Protection/Air Quality Control/Air Pollution; China; cohort studies; confidence interval; Confidence intervals; Death; Density; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Health; Environmental science; Heterogeneity; Industrial pollution; Lung cancer; lung neoplasms; Mortality; odds ratio; pollution; Research Article; Risk; Spatial analysis; Spatial heterogeneity; spatial variation; Spatial variations; Statistical analysis; Suburban areas; Suburbs; Survival analysis; Urban areas; Waste Water Technology; Water Management; Water Pollution Control; Weibull distribution; Weibull statistics; China; Industrial-related pollution; Spatial survival analysis; Traffic-related pollution; Air pollution; Spatial distribution; Lung cancer
• ISSN: 0944-1344; 1614-7499; 1614-7499
• DOI: 10.1007/s11356-021-15438-5

This study aimed to determine the spatial effects of traffic- and industrial-related pollution on the mortality for lung cancer (LC). We conducted a retrospective cohort study by using the data from LC registry in Jiading District for the period from 2002 to 2012. Standard parametric model with Weibull distribution was used for spatial survival analysis. Shorter distance to highway (adjusted odds ratio (aOR) = 1.15, 95% confidence interval (CI): 1.03–1.30) and higher factory density (aOR = 1.20, 95% CI: 1.05–1.37) were significantly associated with an increased risk of LC death, and there was a spatial difference in the associations between northern and southern areas of Jiading District. The risk was high in suburbs as compared with urban areas. Traffic- and industrial-related pollution were significantly associated with an increased risk of LC death, which showed a spatial variation. Further studies are needed to better understand the current LC status in the suburbs and to reduce health disparities.