Definition of pertinent parameters for the evaluation of articular cartilage repair tissue with high-resolution magnetic resonance imaging

• Published in: European journal of radiology Vol. 52; no. 3; pp. 310 - 319
• Main Authors: Marlovits, Stefan, Striessnig, Gabriele, Resinger, Christoph T., Aldrian, Silke M., Vecsei, Vilmos, Imhof, Herwig, Trattnig, Siegfried
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 01.12.2004; Elsevier Science
• Subjects: Adult; Arthroscopy; Biological and medical sciences; Bone Transplantation - pathology; Cartilage - transplantation; Cartilage repair; Cartilage, Articular - pathology; Cartilage, Articular - surgery; Chondrocytes - transplantation; Classification; Female; Femur - pathology; Femur - surgery; Follow-Up Studies; High resolution; Humans; Image Processing, Computer-Assisted - methods; Imaging, Three-Dimensional - methods; Investigative techniques, diagnostic techniques (general aspects); Knee Joint - pathology; Knee Joint - surgery; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Medical sciences; Osteoarticular system. Muscles; Prospective Studies; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Synovitis - diagnosis; Tissue Adhesions - diagnosis; Transplantation, Autologous; Wound Healing; High resolution; Cartilage repair; Magnetic resonance imaging; Classification; Knee; Human; Synovitis; Description; Microfracture; Chondrocyte; Nuclear magnetic resonance imaging; Autograft; Signal; Histopathology; Treatment; Articular cartilage; Graft; Medical imagery; Technique; Repair
• ISSN: 0720-048X; 1872-7727
• DOI: 10.1016/j.ejrad.2004.03.014

To evaluate articular cartilage repair tissue after biological cartilage repair, we propose a new technique of non-invasive, high-resolution magnetic resonance imaging (MRI) and define a new classification system. For the definition of pertinent variables the repair tissue of 45 patients treated with three different techniques for cartilage repair (microfracture, autologous osteochondral transplantation, and autologous chondrocyte transplantation) was analyzed 6 and 12 months after the procedure. High-resolution imaging was obtained with a surface phased array coil placed over the knee compartment of interest and adapted sequences were used on a 1 T MRI scanner. The analysis of the repair tissue included the definition and rating of nine pertinent variables: the degree of filling of the defect, the integration to the border zone, the description of the surface and structure, the signal intensity, the status of the subchondral lamina and subchondral bone, the appearance of adhesions and the presence of synovitis. High-resolution MRI, using a surface phased array coil and specific sequences, can be used on every standard 1 or 1.5 T MRI scanner according to the in-house standard protocols for knee imaging in patients who have had cartilage repair procedures without substantially prolonging the total imaging time. The new classification and grading system allows a subtle description and suitable assessment of the articular cartilage repair tissue.