Alginate Hydrogels as Scaffolds and Delivery Systems to Repair the Damaged Spinal Cord

• Published in: Biotechnology journal Vol. 14; no. 12; pp. e1900275 - n/a
• Main Authors: Grijalvo, Santiago, Nieto‐Díaz, Manuel, Maza, Rodrigo M., Eritja, Ramón, Díaz, David Díaz
• Format: Journal Article
• Language: English
• Published: Germany 01.12.2019
• Subjects: alginate; Alginates - chemistry; Alginates - therapeutic use; Animals; Biocompatible Materials - therapeutic use; biomaterial; Bioprinting; central nervous system; Central Nervous System - injuries; Drug Delivery Systems; Humans; Hydrogels - chemistry; Hydrogels - therapeutic use; Microspheres; neural tissue engineering; Regeneration; Regenerative Medicine; Spinal Cord; Spinal Cord Injuries - therapy; spinal cord injury; Tissue Engineering - methods; Tissue Scaffolds; Wound Healing; alginate; spinal cord injury; neural tissue engineering; biomaterial; regenerative medicine; bioprinting; central nervous system

Alginate (ALG) is a lineal hydrophilic polysaccharide present in brown algae cell walls, which turns into a gel state when hydrated. Gelation readily produces a series of three dimensional (3D) architectures like fibers, capillaries, and microspheres, used as biosensors and bio‐actuators in a pletho...