A Comprehensive Quality Evaluation Method Based on C30-HPLC and an Analytic Hierarchy Process for the Chinese Herbal Formula, Erzhiwan

The quantitative analysis of multiple indexes remains an important quality evaluation method of traditional Chinese medicine (TCM) herbal formulas. The Chinese Pharmacopoeia 2015 only stipulates the content of a single component, specnuezhenide, in Erzhiwan composed of the Fructus Ligustri Lucidi (F...

Full description

Saved in:
Bibliographic Details
Published inMolecules (Basel, Switzerland) Vol. 23; no. 8; p. 2045
Main Authors Nie, Ying, Yao, Weifeng
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 15.08.2018
MDPI
Subjects
Analytic hierarchy process
Antioxidants
C30-HPLC
Chinese medicine
Erzhiwan
Evaluation
herbal formula
Herbal medicine
High-performance liquid chromatography
Isomers
Liquid chromatography
Pharmacology
Powder
Quality
Quality assessment
quality evaluation
Quantitative analysis
Online AccessGet full text

Cover

More Information
Summary:The quantitative analysis of multiple indexes remains an important quality evaluation method of traditional Chinese medicine (TCM) herbal formulas. The Chinese Pharmacopoeia 2015 only stipulates the content of a single component, specnuezhenide, in Erzhiwan composed of the Fructus Ligustri Lucidi (FLL) powder and aqueous extracts of Herba Ecliptae (HE). To generalize the intrinsic quality of Erzhiwan, a novel C30-HPLC method with good precision, accuracy, and reproducibility was developed for the simultaneous determination of six compounds, including two isomers, and then an analytic hierarchy process was further applied to integrate and discriminate the quality of four samples prepared via different methods. The results of the analysis were in agreement with the antioxidant tests in vitro. This comprehensive strategy could provide a reference and suggestions for the improvement of the quality evaluation method of TCM herbal formulas.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Undefined-1
ObjectType-Feature-3
content type line 23
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules23082045