Visible-light-induced surface graft polymerization via camphorquinone impregnation technique

• Published in: Journal of biomedical materials research Vol. 59; no. 2; p. 386
• Main Authors: Ziani-Cherif, Houcine, Abe, Yusuke, Imachi, Kou, Matsuda, Takehisa
• Format: Journal Article
• Language: English
• Published: United States 01.02.2002
• Subjects: Biocompatible Materials - chemical synthesis; Biocompatible Materials - chemistry; Biocompatible Materials - radiation effects; Blood; Heart, Artificial; Humans; In Vitro Techniques; Materials Testing; Photochemistry; Polymers - chemical synthesis; Polymers - chemistry; Polymers - radiation effects; Surface Properties; Terpenes - chemistry
• ISSN: 0021-9304
• DOI: 10.1002/jbm.1254

A surface modification method that is particularly applicable to complexly shaped fabricated devices has long been awaited. In this article, we describe the visible-light-induced surface photograft polymerization technique by which an inner surface of the device is modified by visible-light irradiation through the external surface. Comphorquione, as a photoradical initiator, was impregnated on a segmented polyurethane surface by solvent soaking, followed by visible-light irradiation in the presence of monomers such as acrylamide and poly(ethylene glycol) methacrylate. The resultant surfaces were highly wettable with water, and surface chemical compositional analysis by X-ray photoelectron spectroscopy revealed that the surface was graft-polymerized with these monomers. The simple and widespread applicability of this surface modification technique to biomedical devices is discussed.