Photo-responsive membrane surface: Switching from bactericidal to bacteria-resistant property

• Published in: Materials Science & Engineering C Vol. 84; pp. 52 - 59
• Main Authors: Xie, Yi, Chen, Shengqiu, Qian, Yihui, Zhao, Weifeng, Zhao, Changsheng
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.03.2018; Elsevier BV
• Subjects: Adsorption; Animals; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Antibacterial adhesion; Antifouling; ATRP; Bacteria; Bacterial Adhesion - drug effects; Cattle; Chemical synthesis; Click Chemistry; Contact angle; Escherichia coli - drug effects; Irradiation; Materials science; Membranes, Artificial; Methacrylates - chemistry; Multidrug resistant organisms; Nylons - chemistry; Organic chemistry; Permeability; Photo-responsive membrane surface; Photoelectron Spectroscopy; Polyethersulfones; Polymerization; Polymers - chemistry; Radiation; Serum Albumin, Bovine - chemistry; Sulfones - chemistry; Surface Properties; Ultraviolet radiation; Ultraviolet Rays; X ray photoelectron spectroscopy; Photo-responsive membrane surface; Click chemistry; Antibacterial adhesion; Antifouling; ATRP
• ISSN: 0928-4931; 1873-0191
• DOI: 10.1016/j.msec.2017.11.036

In this paper, a photo-responsive bactericidal and bacteria-resistant membrane was successfully prepared via the integration of atom transfer radical polymerization (ATRP) and click chemistry. Azide-functionalized polycationic poly (N, N-dimethyl-N-(2-(methacryloyloxy)ethyl)-N-((2-nitrobenzyl)oxy)-2-oxoethanaminium bromide) (PDMAEMA-NBE) was synthesized by ATRP. Then, the PDMAEMA-NBE was clicked on alkynyl-functionalized polyethersulfone (PES) membrane surface, and proved by X-ray photoelectron spectrometer (XPS). Upon UV irradiation, the polycationic surface would switch to polyzwitterionic one. Before and after the irradiation, the zeta potentials of the surface altered from +14.7 to −3.8mV, and the water contact angle decreased from 64.0° to 52.7°. The polycationic surface exhibited excellent bactericidal property and the dead bacteria could detach from the polyzwitterionic surface induced by the subsequent UV irradiation. It demonstrated that the designing of photo-responsive membrane surface could be a new strategy for antibacterial adhesion. [Display omitted] •Membranes surface were modified by combining ATRP and click chemistry.•Photo-induced membrane surface potential changed.•Switching from antibacterial to bacteria-resistant membrane surface.