Ball milling: an efficient and green approach for asymmetric organic syntheses
Mechanochemical approaches in an organic synthesis have received increased interest because of their wide applications in green methodologies. Ball milling has been fruitfully utilized in the synthesis of various (elemental) organic scaffolds, including common drugs or drug candidates. However, the...
Saved in:
| Published in | Green chemistry : an international journal and green chemistry resource : GC Vol. 22; no. 2; pp. 32 - 315 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Cambridge
Royal Society of Chemistry
2020
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Summary: | Mechanochemical approaches in an organic synthesis have received increased interest because of their wide applications in green methodologies. Ball milling has been fruitfully utilized in the synthesis of various (elemental) organic scaffolds, including common drugs or drug candidates. However, the utilization of ball milling in asymmetric organic synthesis has not been adequately investigated. Thus, the aim of this review is to highlight the attractive features of the applications of mechanochemistry
via
ball milling in asymmetric organic syntheses in order to attract the attention of a wider section of the synthesis community.
Mechanochemical approaches in an organic synthesis have received increased interest because of their wide applications in green methodologies. |
|---|---|
| Bibliography: | and calix[4]arene chemistry. In 2004, he joined Prof. Pavel Anzenbacher Jr.'s group, where he worked on the interface of photochemistry, synthetic organic chemistry, materials science, and analytical chemistry. In 2010, he moved to Russia and joined as a faculty member in the Department of Organic and Biomolecular Chemistry at the Ural Federal University. In 2012, he earned his DSc in Organic Chemistry. In 2018, he became a Professor of Russian Academy of Science (RAS). His current research interests include the development of novel approaches to new (hetero)aromatic compounds exhibiting biological activity and/or luminescent properties, green chemistry, coordination chemistry, photochemistry, new analytical methods, chemosensors, molecular recognition, and supramolecular chemistry. Sougata Santra received his BSc in Chemistry in 2006 and MSc in 2008 with specialization in Organic Chemistry from Visva-Bharati University, Santiniketan, India. He obtained his PhD in 2014 from the same university under the supervision of Prof. Adinath Majee. Since January 2015, he is working as a post-doctoral researcher in Ural Federal University, Russian Federation, under the supervision of Prof. Grigory V. Zyryanov. In July 2015, he joined the Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, Yekaterinburg, Russian Federation, as a Senior Scientist. His research interest is to develop new methodologies to synthesize heterocyclic compounds along the lines of green chemistry. Currently, he is working on supramolecular chemistry and their syntheses and functionalization. Oleg N. Chupakhin is an Academician of RAS, Head of the Department of Organic and Biomolecular Chemistry at Ural Federal University, and Chief Researcher at the Institute of Organic Synthesis of Ural Branch of RAS. He graduated with honors from Ural Polytechnical Institute (UPI) in 1957. In 1962, he earned his PhD in Organic Chemistry. In 1976, he earned his DSc in Organic Chemistry. His current research interests include new methodologies in organic synthesis, structural analysis of organic compounds, mechanisms of organic reactions, heterocyclic chemistry, green chemistry, industrial chemistry, environmental chemistry, medicinal chemistry, chemosensors, molecular recognition, and supramolecular chemistry. and NO Adinath Majee earned his PhD under the supervision of Prof. Brindaban C. Ranu at the Indian Association for the Cultivation of Science (IACS), Kolkata, in 1998. Then, he joined ENSTA in Paris, France, as a CIES postdoctoral research fellow with Prof. Laurent El Kaim (1999-2000). He joined the Department of Chemistry, Visva-Bharati, Santiniketan, in 2001. He worked in the University of Sheffield, UK, as a BOYSCAST fellow in 2010. He visited ICIQ, Spain, in 2006 and Ural Federal University, Russia, in 2014. Currently, he is a professor in Visva-Bharati University. His research interests include the development of new synthesis methodologies with special emphasis on organocatalysis and green chemistry. Ilya N. Egorov was born in Potsdam, Germany, in 1978. He graduated in 2000 and received his PhD in 2006 from Urals State Technical University (now, UrFU), Ekaterinburg, Russia. His research interests include the development of new synthesis methods for the preparation of synthetically and biologically important heterocycles, including chiral drug candidates and building blocks. . Dmitry S. Kopchuk graduated from the Ural State Technical University (USTU) in 2006. In 2010, he earned his PhD in Organic Chemistry. In 2010, he joined as a Researcher in the Postovsky Institute of Organic Synthesis and in the Department of Organic and Biomolecular Chemistry at the Ural Federal University. His current research interests include the development of novel approaches to new (hetero)aromatic compounds, including new bi- and terpyridine ligands, substituted 1,2,4-triazines Igor S. Kovalev graduated from the Ural Polytechnical Institute (UPI) in 1998. In 2003, he earned his PhD in Organic Chemistry. In 2004, he joined as an Associate Professor in the Department of Organic and Biomolecular Chemistry at the Ural Federal University. His current research interests include the development of novel approaches to new (hetero)aromatic compounds exhibiting biological activity and/or luminescent properties, mass spectrometry, chromatography, green chemistry, coordination chemistry, photochemistry, new analytical methods, chemosensors, molecular recognition, and supramolecular chemistry. 2 etc Vladimir L. Rusinov earned his BS/MS from the Ural Polytechnic University in 1970 and his PhD in Organic Chemistry in 1973. In 1992, he earned his DSc in Organic Chemistry. In 1994-95, he was a visiting professor at the Organic Chemistry Laboratory of Technische Hochschule, Darmstadt, Germany, where he worked with Prof. H. Neunhoeffer. In 2011, he joined the Russian Academy of Sciences (RAS) as a Corresponding Member. Currently, he is the Head of the Organic & Biomolecular Chemistry Department, UrFU. His research interests include the chemistry of nitro (het)aromatic compounds, drug design, medicinal and pharmaceutical chemistry x Grigory V. Zyryanov graduated from Ural Polytechnical Institute (UPI) in 1995. In 2000, he earned his PhD in Organic Chemistry. In 2001-2003, he joined the research group of Prof. Dmitry M. Rudkevich (UT Arlington, Arlington, TX) as a postdoctoral fellow, where he was working in the area of supramolecular chemistry of greenhouse gases (CO Brindaban C. Ranu received his MSc from Calcutta University (India) and obtained his PhD from Jadavpur University (India) in 1982 working with Professor U. R. Ghatak at the Indian Association for the Cultivation of Science. He did his postdoctoral work in Virginia Tech, USA, with Prof. T. Hudlicky during 1982-85 and started independent research at the department of organic chemistry, IACS, from 1985. He became a Professor in 1996 and senior Professor in 2006, and he was the head of the organic chemistry department during 2003-2008. He retired from his regular job in 2013 and is currently continuing as an INSA Senior Scientist (Emeritus). He is a fellow of the Indian Academy of Sciences and Indian National Science Academy. He was offered the J. C. Bose National fellowship by DST, Govt. of India. He received the N. S. Narasimhan Award in 1993 and a bronze medal in 2001 and silver medal in 2009 from the Chemical Research Society of India among others. He is a member of the editorial board of Indian Journal of Chemistry, Section B. He served/is serving as a member in several national and international committees (DST, CSIR, INSA, CRSI, NOST, and IUPAC) in chemical sciences. His research on green synthesis has stimulated considerable interest and inspiration in the chemical sciences community at large. He has recently initiated a research program on visible-light-photocatalyzed reactions and ball-milling-mediated synthesis. He has also edited a book titled "Ball Milling Towards Green Synthesis: Applications, Projects, Challenges" published by the Royal Society of Chemistry in 2015. |
| ISSN: | 1463-9262 1463-9270 |
| DOI: | 10.1039/c9gc03414e |