Childhood diabetes in China. Enormous variation by place and ethnic group

• Published in: Diabetes care Vol. 21; no. 4; pp. 525 - 529
• Main Authors: Yang, Z, Wang, K, Li, T, Sun, W, Li, Y, Chang, Y F, Dorman, J S, LaPorte, R E
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.04.1998
• Subjects: Adolescent; Age Factors; Analysis. Health state; Biological and medical sciences; Child; Child, Preschool; Children & youth; China - epidemiology; Diabetes; Diabetes Mellitus, Type 1 - epidemiology; Epidemiology; Ethnic Groups; Female; General aspects; Geography; Humans; Incidence; Infant; Male; Medical sciences; Minority & ethnic groups; Public health. Hygiene; Public health. Hygiene-occupational medicine; Registries; Research design; Sex Characteristics; Tropical medicine; Asia; China; Endocrinopathy; Human; Immunopathology; Ethnic origin; Autoimmune disease; Korean; Epidemiology; Incidence; Adolescent; Insulin dependent diabetes; Child; Comparative study; Geographical variation
• ISSN: 0149-5992; 1935-5548
• DOI: 10.2337/diacare.21.4.525

Childhood diabetes in China. Enormous variation by place and ethnic group. Z Yang , K Wang , T Li , W Sun , Y Li , Y F Chang , J S Dorman and R E LaPorte Chinese Academy of Preventive Medicine, Beijing, China. Abstract OBJECTIVE: To investigate the incidence rate of IDDM in China. RESEARCH DESIGN AND METHODS: The Chinese IDDM registry was established in 1991 as part of the World Health Organization's Multinational Project for Childhood Diabetes (DiaMond) project. Twenty-two centers were developed to monitor the incidence of IDDM in children < 15 years of age. The population under investigation includes > 20 million individuals, representing approximately 7% of the children in China. Capture-recapture methods were used to estimate the ascertainment. RESULTS: The overall ascertainment-corrected IDDM incidence rate in China was 0.51 per 100,000, the lowest rate ever reported. There was a 12-fold geographic variation (0.13-1.61 per 100,000). In general, the incidence rate was higher in the north and the east. There was a sixfold difference among ethnic groups (highest: Mongol group, 1.82 per 100,000; lowest: Zhuang group, 0.32 per 100,000). CONCLUSIONS: China has an extremely low overall IDDM incidence rate. China also has the greatest geographic and ethnic variation seen for any country.