Diamino- C, N-diarylpyridine positional isomers as inhibitors of lysophosphatidic acid acyltransferase-β
2,6-Diamino-4, N-diarylpyridines were identified as potent, isoform selective inhibitors of the enzymatic activity of lysophosphatidic acid acyltransferase-β (LPAAT-β).
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Published in | Bioorganic & medicinal chemistry letters Vol. 15; no. 21; pp. 4703 - 4707 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Elsevier Ltd
01.11.2005
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | 2,6-Diamino-4,
N-diarylpyridines were identified as potent, isoform selective inhibitors of the enzymatic activity of lysophosphatidic acid acyltransferase-β (LPAAT-β). |
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ISSN: | 0960-894X 1464-3405 |
DOI: | 10.1016/j.bmcl.2005.07.055 |