Synthesis of silver-cerium titanate nanotubes and their surface properties and antibacterial applications

• Published in: Materials Science & Engineering C Vol. 115; p. 111051
• Main Authors: Sales, Débora A., Marques, Thalles M.F., Ghosh, Anupama, Gusmão, Suziete B.S., Vasconcelos, Thiago L., Luz-Lima, Cleanio, Ferreira, Odair P., Hollanda, Luciana M., Lima, Idglan S., Silva-Filho, Edson C., Dittz, Dalton, Lobo, Anderson O., Viana, Bartolomeu C.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2020; Elsevier BV
• Subjects: Adhesion; Anatase; Animals; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Antibacterial activity; Biological properties; Cell adhesion; Cell adhesion & migration; Cell Line; Cerium; Cerium - chemistry; Cerium oxides; Cytotoxicity; Escherichia coli; Heterostructures; Interlayers; Ion exchange; Materials science; Metal Nanoparticles - chemistry; Mice; Microbial Sensitivity Tests; Microbial Viability - drug effects; Nanoparticles; Nanotechnology; Nanotubes; Nanotubes - chemistry; Oxidation; Particle Size; Silver; Silver - chemistry; Staphylococcus aureus - drug effects; Surface Properties; Synthesis; Titanate nanotubes; Titanium - chemistry; Titanium dioxide; Toxicity; Valence; Cerium; Silver; Antibacterial activity; Titanate nanotubes; Ion exchange
• ISSN: 0928-4931; 1873-0191
• DOI: 10.1016/j.msec.2020.111051

Nano-heterostructures of titanate nanotubes were synthesized and they revealed a complex structure with the formation of TiO2 (anatase), CeO2, Ag2O and metallic silver nanoparticles on the outer walls and intercalation of Ce4+ and Ag+ into the interlayer spaces of the nanotubes by microwave-assisted hydrothermal process and subjected to ion exchange reactions. To the best of our knowledge, this is the first reported silver and cerium co-exchanged titanate nanotubes for bio-applications. The co-ion exchange processes preserved the original tubular structure of titanate nanotubes with significant changes of the superficial as well as interlamellar environment. This study opens up possibility of synthesizing complex, functional nano-heterostructure with the scope of modification of the final structure, especially the amount and oxidation state of the intercalated cation (Ce4+, Ce3+ and Ag+) as well as the quantity and variety of the decorating nanoparticles (CeO2, Ag2O or metallic Ag). The interplay of which, in turn, can lead to important biological properties and applications, owing to their ion-liberation capacity. The samples were tested in antibacterial activity with two different kind of bacteria (gram positive and negative), cell cytotoxicity and adhesion, and it was found that the nano-heterostructure formed shows high antibacterial activity with low cytotoxicity and high cell adhesion, which makes it a promising material for further health applications. •Structural and Antibacterial properties of titanate nano-heterostructures prepared by microwave assisted hydrothermal method;•Titanate nanotubes are decorated with anatase nanoparticles and CeO2, Ag2O or metallic Ag nanoparticles;•Antibacterial activity (gram positive and negative), low cell cytotoxicity and high cell adhesion.