Polymersomes with aggregation-induced emission based on amphiphilic block copolypeptoids

Biocompatible polymersomes are prepared from amphiphilic block copolypeptoids with aggregation-induced emission, where the hydrophobic block P(TPE-NAG) is a tetraphenylethylene (TPE)-modified poly( N -allylglycine) and the hydrophilic block is polysarcosine. These nanoparticles are non-cytotoxic and...

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Published inChemical communications (Cambridge, England) Vol. 55; no. 9; pp. 1353 - 13533
Main Authors Tao, Xinfeng, Chen, Hui, Trépout, Sylvain, Cen, Jiayu, Ling, Jun, Li, Min-Hui
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 07.11.2019
Subjects
Agglomeration
Aqueous solutions
Biocompatibility
Chemical Sciences
Emission
Fluorescence
Nanoparticles
Polymers
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Summary:Biocompatible polymersomes are prepared from amphiphilic block copolypeptoids with aggregation-induced emission, where the hydrophobic block P(TPE-NAG) is a tetraphenylethylene (TPE)-modified poly( N -allylglycine) and the hydrophilic block is polysarcosine. These nanoparticles are non-cytotoxic and show strong fluorescence emission in aqueous solution. Fluorescent and biocompatible polymersomes based on the amphiphilic block copolypeptoid P(TPE-NAG)- b -PSar are promising for bio-imaging and drug delivery applications.
Bibliography:10.1039/c9cc07501a
Electronic supplementary information (ESI) available. See DOI
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc07501a