Antimicrobial prophylaxis of infection

Antimicrobial agents are used to prevent infections in a variety of clinical circumstances. In certain instances, the precise indications for prophylaxis remain controversial, and the preferred regimens undergo alterations based upon evolving clinical experience, changing patterns of microbial susce...

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Bibliographic Details
Published inInfectious disease clinics of North America Vol. 9; no. 3; p. 783
Main Authors Dickinson, G M, Bisno, A L
Format Journal Article
LanguageEnglish
Published United States 01.09.1995
Subjects
Antibiotic Prophylaxis
Endocarditis, Bacterial - prevention & control
Haemophilus Infections - prevention & control
Humans
Meningococcal Infections - prevention & control
Rheumatic Fever - prevention & control
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Summary:Antimicrobial agents are used to prevent infections in a variety of clinical circumstances. In certain instances, the precise indications for prophylaxis remain controversial, and the preferred regimens undergo alterations based upon evolving clinical experience, changing patterns of microbial susceptibility, and innovations in medical and surgical practice. This article outlines the general principles underlying the use of antimicrobial prophylaxis and presents recommendations for the use of such prophylaxis in three areas: (1) surgery involving contaminated, clean-contaminated, and clean procedures; (2) prevention of infections due to specific pathogens, including Neisseria meningitidis, Hemophilus influenzae, Streptococcus pneumoniae, and Streptococcus pyogenes; and (3) prevention of infective endocarditis.
ISSN:0891-5520
DOI:10.1016/S0891-5520(20)30697-8