Rhythm Control in Atrial Fibrillation — One Setback after Another

Atrial fibrillation, the most common sustained arrhythmia observed in hospitalized patients, is associated with substantial morbidity, and its occurrence approximately doubles the rate of death as compared with that of patients in whom sinus rhythm is maintained. The global effect of atrial fibrilla...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 358; no. 25; pp. 2725 - 2727
Main Authors Cain, Michael E, Curtis, Anne B
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 19.06.2008
Subjects
Anti-Arrhythmia Agents - adverse effects
Anti-Arrhythmia Agents - therapeutic use
Atrial Fibrillation - prevention & control
Cardiac arrhythmia
Cardiology
Cardiovascular Diseases - mortality
Combined Modality Therapy
Electric Countershock
Heart failure
Heart Failure - therapy
Heart Rate
Humans
Medical research
Medical treatment
Treatment Failure
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Summary:Atrial fibrillation, the most common sustained arrhythmia observed in hospitalized patients, is associated with substantial morbidity, and its occurrence approximately doubles the rate of death as compared with that of patients in whom sinus rhythm is maintained. The global effect of atrial fibrillation on public health is so great that international professional organizations have integrated the results of seminal studies to progressively formulate data-driven management guidelines. 1 Patients with heart failure are at increased risk for atrial fibrillation and constitute an important subgroup of all patients with this arrhythmia. Data from trials involving patients with atrial fibrillation have shown that a . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMe0803289