Reversible 18-FDG-uptake defects on myocardial PET: Is this myocardial resurrection?

Abstract Because it can accurately detect preserved glucose metabolism even in the hypoperfused or stunned myocardium, 18-FDG-PET is considered as the gold standard of myocardial viability assessment. In tako-tsubo cardiomyopathy, a presumed condition of stunning, absence of glucose metabolism howev...

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Published inInternational journal of cardiology Vol. 127; no. 3; pp. e175 - e178
Main Authors De Boeck, Bart W.L, Verburg, Frederik A, Hobbelink, Monique G.G, Velthuis, Birgitta, Melman, Paul G, Cramer, Maarten-Jan M
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ireland Ltd 21.07.2008
Subjects
Aged
Cardiovascular
Echocardiography
Female
Fluorodeoxyglucose F18 - metabolism
Humans
Myocardial Stunning - diagnosis
Myocardial Stunning - diagnostic imaging
Myocardial Stunning - metabolism
Myocardium - metabolism
PET
Positron-Emission Tomography - methods
Scintigraphy
Tako-Tsubo cardiomyopathy
Tomography, Emission-Computed, Single-Photon - methods
Viability
Tako-Tsubo cardiomyopathy
Echocardiography
Scintigraphy
Viability
PET
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Summary:Abstract Because it can accurately detect preserved glucose metabolism even in the hypoperfused or stunned myocardium, 18-FDG-PET is considered as the gold standard of myocardial viability assessment. In tako-tsubo cardiomyopathy, a presumed condition of stunning, absence of glucose metabolism however is not a marker of death. This sheds a critical light on 18-FDG-PET as a gold standard for viability.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2007.05.046