Sourcing Photoreceptor-like Cells for Treating Vision Loss

Loss of retinal photoreceptor cells is a critical event in loss of vision. A new, albeit tentative, strategy to rectify the loss of photoreceptor cells involves reprogramming fibroblasts into chemically induced photoreceptor-like cells.

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Bibliographic Details
Published inThe New England journal of medicine Vol. 383; no. 19; pp. 1888 - 1890
Main Author Apte, Rajendra S
Format Journal Article
LanguageEnglish
Published Boston Massachusetts Medical Society 05.11.2020
Subjects
Fibroblasts
Gene therapy
Genetic engineering
Mutation
Photoreceptors
Regulatory approval
Retina
Stem cells
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Summary:Loss of retinal photoreceptor cells is a critical event in loss of vision. A new, albeit tentative, strategy to rectify the loss of photoreceptor cells involves reprogramming fibroblasts into chemically induced photoreceptor-like cells.
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMcibr2027602