A novel electrochemiluminescence strategy for ultrasensitive DNA assay using luminol functionalized gold nanoparticles multi-labeling and amplification of gold nanoparticles and biotin-streptavidin system

Luminol functionalized gold nanoparticles were used as labels for electrochemiluminescence signal amplification and an ultrasensitive, highly selective, convenient, low cost DNA detection strategy was developed.

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 46; no. 40; pp. 7560 - 7562
Main Authors Chai, Ying, Tian, Dayong, Wang, Wei, Cui, Hua
Format Journal Article
LanguageEnglish
Published England 01.01.2010
Subjects
Base Sequence
Biosensing Techniques - economics
Biosensing Techniques - methods
Biotin - chemistry
DNA - analysis
Electrochemistry - economics
Electrochemistry - methods
Gold - chemistry
Humans
Luminescent Measurements - economics
Luminescent Measurements - methods
Luminol - chemistry
Nanoparticles - chemistry
Sensitivity and Specificity
Serum - chemistry
Streptavidin - chemistry
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Summary:Luminol functionalized gold nanoparticles were used as labels for electrochemiluminescence signal amplification and an ultrasensitive, highly selective, convenient, low cost DNA detection strategy was developed.
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ISSN:1359-7345
1364-548X
DOI:10.1039/c0cc02356f