Serum copper and zinc concentrations in patients with chronic hepatitis B
The aim of this study was to measure the alterations in serum trace elements, including zinc and copper in patients with chronic hepatitis and to compare with the results of healthy individuals. The serum zinc and copper concentrations were measured by using atomic absorption spectrophotometer in se...
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Published in | The Journal of infection Vol. 51; no. 1; pp. 38 - 40 |
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Main Authors | , , , , |
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Language | English |
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01.07.2005
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Abstract | The aim of this study was to measure the alterations in serum trace elements, including zinc and copper in patients with chronic hepatitis and to compare with the results of healthy individuals. The serum zinc and copper concentrations were measured by using atomic absorption spectrophotometer in sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. One hundred and five subjects, 71 patients with chronic hepatitis B (46 asymptomatic carriers, 25 chronic active hepatitis B) and 34 healthy individuals were included in this study. Sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. Serum zinc concentrations were 104±24.98μg/dl in asymptomatic carriers, 97±16.03μg/dl in chronic active hepatitis and 108±21.07 in healthy controls, respectively. Serum copper concentrations were 88±17.8μg/dl in asymptomatic carriers, 86±20.02μg/dl in patients with chronic active hepatitis B and 88±13.59μg/dl in healthy controls, respectively. Serum zinc and copper concentrations were not statistically different in patients with chronic hepatitis B compared with those of healthy individuals (p>0.05). Serum trace element concentrations did not show statistical alterations in patients with chronic hepatitis B compared with healthy subjects. |
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AbstractList | The aim of this study was to measure the alterations in serum trace elements, including zinc and copper in patients with chronic hepatitis and to compare with the results of healthy individuals. The serum zinc and copper concentrations were measured by using atomic absorption spectrophotometer in sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. One hundred and five subjects, 71 patients with chronic hepatitis B (46 asymptomatic carriers, 25 chronic active hepatitis B) and 34 healthy individuals were included in this study. Sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. Serum zinc concentrations were 104+/-24.98 microg/dl in asymptomatic carriers, 97+/-16.03 microg/dl in chronic active hepatitis and 108+/-21.07 in healthy controls, respectively. Serum copper concentrations were 88+/-17.8 microg/dl in asymptomatic carriers, 86+/-20.02 microg/dl in patients with chronic active hepatitis B and 88+/-13.59 microg/dl in healthy controls, respectively. Serum zinc and copper concentrations were not statistically different in patients with chronic hepatitis B compared with those of healthy individuals (p>0.05). Serum trace element concentrations did not show statistical alterations in patients with chronic hepatitis B compared with healthy subjects. The aim of this study was to measure the alterations in serum trace elements, including zinc and copper in patients with chronic hepatitis and to compare with the results of healthy individuals. The serum zinc and copper concentrations were measured by using atomic absorption spectrophotometer in sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. One hundred and five subjects, 71 patients with chronic hepatitis B (46 asymptomatic carriers, 25 chronic active hepatitis B) and 34 healthy individuals were included in this study. Sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. Serum zinc concentrations were 104+/-24.98 microg/dl in asymptomatic carriers, 97+/-16.03 microg/dl in chronic active hepatitis and 108+/-21.07 in healthy controls, respectively. Serum copper concentrations were 88+/-17.8 microg/dl in asymptomatic carriers, 86+/-20.02 microg/dl in patients with chronic active hepatitis B and 88+/-13.59 microg/dl in healthy controls, respectively. Serum zinc and copper concentrations were not statistically different in patients with chronic hepatitis B compared with those of healthy individuals (p>0.05). Serum trace element concentrations did not show statistical alterations in patients with chronic hepatitis B compared with healthy subjects. The aim of this study was to measure the alterations in serum trace elements, including zinc and copper in patients with chronic hepatitis and to compare with the results of healthy individuals. The serum zinc and copper concentrations were measured by using atomic absorption spectrophotometer in sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. One hundred and five subjects, 71 patients with chronic hepatitis B (46 asymptomatic carriers, 25 chronic active hepatitis B) and 34 healthy individuals were included in this study. Sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. Serum zinc concentrations were 104±24.98μg/dl in asymptomatic carriers, 97±16.03μg/dl in chronic active hepatitis and 108±21.07 in healthy controls, respectively. Serum copper concentrations were 88±17.8μg/dl in asymptomatic carriers, 86±20.02μg/dl in patients with chronic active hepatitis B and 88±13.59μg/dl in healthy controls, respectively. Serum zinc and copper concentrations were not statistically different in patients with chronic hepatitis B compared with those of healthy individuals (p>0.05). Serum trace element concentrations did not show statistical alterations in patients with chronic hepatitis B compared with healthy subjects. |
Author | Tezeren, Deniz Kavas, Guzin Ozelcı Cebecı, Sevsen Altınay Cesur, Salih Aksaray, Sebahat |
Author_xml | – sequence: 1 givenname: Salih surname: Cesur fullname: Cesur, Salih email: scesur89@yahoo.com organization: Refik Saydam Hygiene Centre, Tuberculosis Reference and Research Laboratory, Ankara, Turkey – sequence: 2 givenname: Sevsen Altınay surname: Cebecı fullname: Cebecı, Sevsen Altınay organization: Department of Pathophysiology, School of Medicine, Ankara University, Ankara, Turkey – sequence: 3 givenname: Guzin Ozelcı surname: Kavas fullname: Kavas, Guzin Ozelcı organization: Department of Pathophysiology, School of Medicine, Ankara University, Ankara, Turkey – sequence: 4 givenname: Sebahat surname: Aksaray fullname: Aksaray, Sebahat organization: Department of Microbiology and Clinical Microbiology, Ankara Numune Training and Research Hospital, Ankara, Turkey – sequence: 5 givenname: Deniz surname: Tezeren fullname: Tezeren, Deniz organization: Department of Microbiology and Clinical Microbiology, Ankara Numune Training and Research Hospital, Ankara, Turkey |
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Cites_doi | 10.1385/BTER:90:1-3:31 10.1248/bpb.25.426 10.1007/BF02365444 10.1016/S0946-672X(02)80049-9 10.1016/S0946-672X(98)80020-5 10.1046/j.1440-1746.2000.02199.x |
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Keywords | Control Chronic active hepatitis Asymptomatic carriers Copper Zinc Infection Human Viral hepatitis B Viral disease Digestive diseases Hepatic disease Serum Concentration |
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References_xml | – volume: 16 start-page: 227 year: 2002 end-page: 230 ident: bib6 article-title: Trace elements in viral hepatitis publication-title: J Trace Elem Med Biol contributor: fullname: Avci – volume: 29 start-page: 610 year: 1994 end-page: 615 ident: bib5 article-title: Serum trace metals in chronic viral hepatitis and hepatocellular carcinoma in Thailand publication-title: J Gastroenterol contributor: fullname: Komindr – start-page: 33 year: 1996 ident: bib4 publication-title: Akut B hepatitinde ve asemptomatik HbsAg taşıyıcılarda plazma ve eritrosit çinko düzeyleri. III. Ulusal Viral Hepatit Sempozyumu, 7-9 Kasım 1996 contributor: fullname: Alpagut – volume: 90 start-page: 31 year: 2002 end-page: 38 ident: bib8 article-title: Serum zinc as a factor predicting response to interferon-alpha2b therapy in children with chronic hepatitis B publication-title: Biol Trace Elem Res contributor: fullname: Kasirga – volume: 27 start-page: 476 year: 1996 end-page: 480 ident: bib7 article-title: Serum trace metal levels in patients with acute hepatitis B publication-title: Southeast Asian J Trop Med Public Health contributor: fullname: Kurathong – volume: 12 start-page: 44 year: 1998 end-page: 49 ident: bib9 article-title: Serum zinc and copper concentrations and Cu/Zn ratios in patients with hepatopathies or diabetes publication-title: J Trace Elem Med Biol contributor: fullname: Martin-Logos – volume: 54 start-page: 85 year: 1996 end-page: 92 ident: bib1 article-title: Liver disease and essential trace elements publication-title: Nippon Rinsho contributor: fullname: Arakawa – volume: 15 start-page: 786 year: 2000 end-page: 791 ident: bib3 article-title: Accumulation of copper in the liver and hepatic injury in chronic hepatitis C publication-title: J Gastroenterol Hepatol contributor: fullname: Fukuda – volume: 25 start-page: 426 year: 2002 end-page: 431 ident: bib2 article-title: A new diagnostic method for chronic hepatitis, liver cirrhosis and hepatocellular carcinoma based on serum metallothionein, copper, and zinc level publication-title: Biol Pharm Bull contributor: fullname: Ebara – start-page: 33 year: 1996 ident: 10.1016/j.jinf.2004.08.012_bib4 contributor: fullname: Yıldırmak – volume: 90 start-page: 31 year: 2002 ident: 10.1016/j.jinf.2004.08.012_bib8 article-title: Serum zinc as a factor predicting response to interferon-alpha2b therapy in children with chronic hepatitis B publication-title: Biol Trace Elem Res doi: 10.1385/BTER:90:1-3:31 contributor: fullname: Ozbal – volume: 25 start-page: 426 year: 2002 ident: 10.1016/j.jinf.2004.08.012_bib2 article-title: A new diagnostic method for chronic hepatitis, liver cirrhosis and hepatocellular carcinoma based on serum metallothionein, copper, and zinc level publication-title: Biol Pharm Bull doi: 10.1248/bpb.25.426 contributor: fullname: Nakayama – volume: 27 start-page: 476 year: 1996 ident: 10.1016/j.jinf.2004.08.012_bib7 article-title: Serum trace metal levels in patients with acute hepatitis B publication-title: Southeast Asian J Trop Med Public Health contributor: fullname: Pramoolsinsap – volume: 29 start-page: 610 year: 1994 ident: 10.1016/j.jinf.2004.08.012_bib5 article-title: Serum trace metals in chronic viral hepatitis and hepatocellular carcinoma in Thailand publication-title: J Gastroenterol doi: 10.1007/BF02365444 contributor: fullname: Pramoolsinsap – volume: 16 start-page: 227 issue: 4 year: 2002 ident: 10.1016/j.jinf.2004.08.012_bib6 article-title: Trace elements in viral hepatitis publication-title: J Trace Elem Med Biol doi: 10.1016/S0946-672X(02)80049-9 contributor: fullname: Kalkan – volume: 12 start-page: 44 year: 1998 ident: 10.1016/j.jinf.2004.08.012_bib9 article-title: Serum zinc and copper concentrations and Cu/Zn ratios in patients with hepatopathies or diabetes publication-title: J Trace Elem Med Biol doi: 10.1016/S0946-672X(98)80020-5 contributor: fullname: Teres-Martos – volume: 54 start-page: 85 year: 1996 ident: 10.1016/j.jinf.2004.08.012_bib1 article-title: Liver disease and essential trace elements publication-title: Nippon Rinsho contributor: fullname: Suziki – volume: 15 start-page: 786 year: 2000 ident: 10.1016/j.jinf.2004.08.012_bib3 article-title: Accumulation of copper in the liver and hepatic injury in chronic hepatitis C publication-title: J Gastroenterol Hepatol doi: 10.1046/j.1440-1746.2000.02199.x contributor: fullname: Hatano |
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SubjectTerms | Asymptomatic carriers Biological and medical sciences Chronic active hepatitis Control Copper Copper - blood Female Hepatitis B, Chronic - blood Human viral diseases Humans Infectious diseases Male Medical sciences Viral diseases Viral hepatitis Zinc Zinc - blood |
Title | Serum copper and zinc concentrations in patients with chronic hepatitis B |
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