Serum copper and zinc concentrations in patients with chronic hepatitis B

• Published in: The Journal of infection Vol. 51; no. 1; pp. 38 - 40
• Main Authors: Cesur, Salih, Cebecı, Sevsen Altınay, Kavas, Guzin Ozelcı, Aksaray, Sebahat, Tezeren, Deniz
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.07.2005; Elsevier
• Subjects: Asymptomatic carriers; Biological and medical sciences; Chronic active hepatitis; Control; Copper; Copper - blood; Female; Hepatitis B, Chronic - blood; Human viral diseases; Humans; Infectious diseases; Male; Medical sciences; Viral diseases; Viral hepatitis; Zinc; Zinc - blood; Control; Chronic active hepatitis; Asymptomatic carriers; Copper; Zinc; Infection; Human; Viral hepatitis B; Viral disease; Digestive diseases; Hepatic disease; Serum; Concentration
• ISSN: 0163-4453; 1532-2742
• DOI: 10.1016/j.jinf.2004.08.012

The aim of this study was to measure the alterations in serum trace elements, including zinc and copper in patients with chronic hepatitis and to compare with the results of healthy individuals. The serum zinc and copper concentrations were measured by using atomic absorption spectrophotometer in sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. One hundred and five subjects, 71 patients with chronic hepatitis B (46 asymptomatic carriers, 25 chronic active hepatitis B) and 34 healthy individuals were included in this study. Sera of patients with chronic hepatitis and statistically compared with those of healthy individuals. Serum zinc concentrations were 104±24.98μg/dl in asymptomatic carriers, 97±16.03μg/dl in chronic active hepatitis and 108±21.07 in healthy controls, respectively. Serum copper concentrations were 88±17.8μg/dl in asymptomatic carriers, 86±20.02μg/dl in patients with chronic active hepatitis B and 88±13.59μg/dl in healthy controls, respectively. Serum zinc and copper concentrations were not statistically different in patients with chronic hepatitis B compared with those of healthy individuals (p>0.05). Serum trace element concentrations did not show statistical alterations in patients with chronic hepatitis B compared with healthy subjects.