An overview of lipid membrane supported by colloidal particles

• Published in: Advances in colloid and interface science Vol. 133; no. 1; pp. 1 - 21
• Main Authors: Troutier, Anne-Lise, Ladavière, Catherine
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 31.05.2007; Elsevier
• Subjects: Chemical Sciences; Chemistry; Colloidal state and disperse state; Colloids; Electrolytes; Exact sciences and technology; General and physical chemistry; Interface; Lipid adsorption; Lipid/Particle interactions; Lipids; Lipids - chemistry; Membranes; Micro–submicro-nanoparticles; Particle Size; Physical and chemical studies. Granulometry. Electrokinetic phenomena; Polymers; Silicon Dioxide - chemistry; Surface physical chemistry; TAP; 6-CF; PS; RNA; IgE; AFM; SMBV; Lipids; DO; DP; MBMA; DS; NBD; AMA; DSC; DODAC; DODAB; FRAP; FRET; MBP; XPS; DiIC 16; T m; Di6ASP-BS, N-(3-sulfopropyl)-4-(4-(didecylamino) styryl) pyridinium; Lipid adsorption; CSLM; Micro–submicro-nanoparticles; Lipid/Particle interactions; PSS; NMR; Lipid chain lengths:DM; PEG; PC; Lipid head groups:PA; PE; PAH; SSV; PG; PVA; DPH; TEM; Other lipids:DHDAB; Interface; ELISA; PO; Adsorption; Support; Nanoparticle; Micro-submicro-nanoparticles; Particle interaction; Membrane; Review; Colloid particle
• ISSN: 0001-8686; 1873-3727
• DOI: 10.1016/j.cis.2007.02.003

In recent years, original hybrid assemblies composed of a particle core surrounded by a lipid shell emerged as promising entities for various biotechnological applications. Their broadened bio-potentialities, ranging from model membrane systems or biomolecule screening supports, to substance delivery reservoirs or therapeutic vectors, are furthered by their versatility of composition due to the possible wide variation in the particle nature and size, as well as in the lipid formulation. The synthesis, the characteristics, and the uses of these Lipid/Particle assemblies encountered in the literature so far are reviewed, and classified according to the spherical core size in order to highlight general trends. Moreover, several criteria are particularly discussed: i) the interactions involved between the particles and the lipids, and implicitly the assembly elaboration mechanism, ii) the most suited techniques for an accurate characterization of the entities from structural and physicochemical points of view, and iii) the remarkable properties of the solid-supported lipid membrane obtained.