Chronic Cavitary Pulmonary Aspergillosis: A Case Report and Review of the Literature

BACKGROUND Aspergillus spores have the ability to affect patients with or without intact immune systems; because of this disease's wide patient involvement it deserves a place on the differential diagnosis list, with endocarditis and tuberculosis, for those presenting with new pulmonary nodules...

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Published inThe American journal of case reports Vol. 20; pp. 1220 - 1224
Main Authors Graham, Kathryn G, Nasir, Asad
Format Journal Article
LanguageEnglish
Published United States International Scientific Literature, Inc 18.08.2019
Subjects
Aged
Alcoholism - complications
Aspergillus fumigatus - isolation & purification
Carcinogens - toxicity
Chronic Disease
Delayed Diagnosis
Diagnosis, Differential
Female
Glucocorticoids - therapeutic use
Humans
Lung - diagnostic imaging
Occupational Exposure - adverse effects
Pulmonary Aspergillosis - diagnosis
Pulmonary Disease, Chronic Obstructive - complications
Pulmonary Disease, Chronic Obstructive - drug therapy
Tetrachloroethylene - toxicity
Tomography, X-Ray Computed
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Summary:BACKGROUND Aspergillus spores have the ability to affect patients with or without intact immune systems; because of this disease's wide patient involvement it deserves a place on the differential diagnosis list, with endocarditis and tuberculosis, for those presenting with new pulmonary nodules or cavitation. CASE REPORT This case report involves the presentation, diagnosis, and treatment of a 69-year-old female who presented with new rapidly progressing cavitary lung lesions in the setting of copious administration of systemic steroid use. Given the patient's past history of alcoholism and environmental exposure, her case was not straight forward in regard to a diagnosis. Ultimately, she was diagnosed with chronic cavity pulmonary aspergillosis in the setting of chronic immunosuppression secondary to systemic steroid administration. Due to her convoluted medical history and the poor differential diagnosis list, there was a delay in final diagnosis. CONCLUSIONS This case report and clinical review aims to prevent anchoring when the patient's presentation is not straight forward and aims to remind the clinician of the importance of a differential diagnosis.
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Authors’ Contribution
Conflict of interest: None declared
Data Interpretation
Literature Search
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Study Design
Manuscript Preparation
Statistical Analysis
ISSN:1941-5923
1941-5923
DOI:10.12659/AJCR.915893