Surgical Excision with Rotational Flap Reconstruction for Basosquamous Cell Carcinoma in Xeroderma Pigmentosa: A Case Report

Xeroderma pigmentosa (XP) is a rare autosomal recessive disorder which is characterized by a defect in nucleotide excision repair of DNA following exposure to UV radiation. This leads to hypersensitivity to sunlight causing pigmented skin lesions, photophobia and a 1000-fold increase in risk of deve...

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Published inIndian journal of otolaryngology, and head, and neck surgery Vol. 71; no. Suppl 1; pp. 702 - 705
Main Authors Malipatil, Sharanabasappa Rudragouda, Jonnalagadda, Sriharsha Vijay
Format Journal Article
LanguageEnglish
Published New Delhi Springer India 01.10.2019
Springer Nature B.V
Subjects
Case reports
Clinical Report
DNA repair
Head & neck cancer
Head and Neck Surgery
Medicine
Medicine & Public Health
Otorhinolaryngology
Skin cancer
Tumors
Rotational flap
Xeroderma pigmentosa
Basal cell carcinoma
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Summary:Xeroderma pigmentosa (XP) is a rare autosomal recessive disorder which is characterized by a defect in nucleotide excision repair of DNA following exposure to UV radiation. This leads to hypersensitivity to sunlight causing pigmented skin lesions, photophobia and a 1000-fold increase in risk of developing cutaneous malignancies like basal cell carcinomas, squamous cell carcinomas and melanomas of head and neck. We present an interesting case of a 28 year old man with basosquamous cell carcinoma secondary to XP treated successfully with surgical excision and reconstruction with rotational flap technique.
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ISSN:2231-3796
0973-7707
DOI:10.1007/s12070-018-1508-z