No associations between self-reported knee joint instability and radiographic features in knee osteoarthritis patients prior to Total Knee Arthroplasty: A cross-sectional analysis of the Longitudinal Leiden Orthopaedics Outcomes of Osteo-Arthritis study (LOAS) data

• Published in: The knee Vol. 24; no. 4; pp. 816 - 823
• Main Authors: Leichtenberg, Claudia S., Meesters, Jorit J.L., Kroon, Herman M., Verdegaal, Suzan H.M., Tilbury, Claire, Dekker, Joost, Nelissen, Rob G.H.H., Vliet Vlieland, Thea P.M., van der Esch, Martin
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2017; Elsevier Limited
• Subjects: Aged; Arthritis; Arthroplasty (knee); Arthroplasty, Replacement, Knee; Cohort Studies; Consent; Cross-Sectional Studies; Female; Humans; Hypotheses; Joint Instability - complications; Joint Instability - diagnostic imaging; Joint Instability - epidemiology; Joint surgery; Knee; Knee Joint - diagnostic imaging; Knee Joint - pathology; Knee Joint - surgery; Knee joint instability; Longitudinal Studies; Male; Middle Aged; Osteoarthritis; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - diagnostic imaging; Osteoarthritis, Knee - surgery; Pain; Prevalence; Prospective Studies; Questionnaires; Radiology; Regression Analysis; Self Report; Surgery; Total knee replacement; Radiology; Knee joint instability; Total knee replacement; Osteoarthritis
• ISSN: 0968-0160; 1873-5800
• DOI: 10.1016/j.knee.2017.04.001

To describe the prevalence of self-reported knee joint instability in patients with pre-surgery knee osteoarthritis (OA) and to explore the associations between self-reported knee joint instability and radiological features. A cross-sectional study including patients scheduled for primary Total Knee Arthroplasty (TKA). Self-reported knee instability was examined by questionnaire. Radiological features consisted of osteophyte formation and joint space narrowing (JSN), both scored on a 0 to three scale. Scores >1 are defined as substantial JSN or osteophyte formation. Regression analyses were provided to identify associations of radiological features with self-reported knee joint instability. Two hundred and sixty-five patients (mean age 69years and 170 females) were included. Knee instability was reported by 192 patients (72%). Substantial osteophyte formation was present in 78 patients (41%) reporting and 33 patients (46%) not reporting knee joint instability. Substantial JSN was present in 137 (71%) and 53 patients (73%), respectively. Self-reported knee instability was not associated with JSN (relative to score 0, odds ratios (95% CI) of score 1, 2 and 3 were 0.87 (0.30–2.54), 0.98 (0.38–2.52), 0.68 (0.25–1.86), respectively) or osteophyte formation (relative to score 0, odds ratios (95% CI) of score 1, 2 and 3 were 0.77 (0.36–1.64), 0.69 (0.23–1.45), 0.89 (0.16–4.93), respectively). Stratified analysis for pain, age and BMI showed no associations between self-reported knee joint instability and radiological features. Self-reported knee joint instability is not associated with JSN or osteophyte formation.