Cholesterol Granulomas in Three Meerkats (Suricata suricatta)

Cholesterol granulomas are uncommon pathologic lesions in animals, although they are important intracranial tumors in humans. This report describes cholesterol granulomas associated with multiple organ systems of three captive meerkats. In the most severe case, meerkat No. 1, the pathologic behavior...

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Published inVeterinary pathology Vol. 37; no. 6; pp. 684 - 686
Main Authors Sladky, K. K., Dalldorf, F. G., Steinberg, H., Wright, J. F., Loomis, M. R.
Format Journal Article
LanguageEnglish
Published Los Angeles, CA SAGE Publications 01.11.2000
Subjects
Animals
Brain - pathology
Carnivora
Cholesterol
Fatal Outcome
Granuloma - pathology
Granuloma - veterinary
Male
Granuloma
Cerebral
zoo
Meerkat
Cholesterol
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Summary:Cholesterol granulomas are uncommon pathologic lesions in animals, although they are important intracranial tumors in humans. This report describes cholesterol granulomas associated with multiple organ systems of three captive meerkats. In the most severe case, meerkat No. 1, the pathologic behavior of the cholesterol granuloma was unique in that it appeared to locally invade the cerebrum and calvarium, possibly contributing to neurological deficits observed antemortem. A review of other meerkat necropsies revealed incidental, asymptomatic cholesterol granulomas in organs of two other individuals, meerkat Nos. 2 and 3. Histologically, all lesions were composed of cholesterol clefts admixed with large, foamy macrophages containing hemosiderin, multinucleated giant cells, lymphocytes, plasma cells, and foci of mineralization. Hypercholesterolemia was documented in two of the three meerkats.
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ISSN:0300-9858
1544-2217
DOI:10.1354/vp.37-6-684