Soft tissue small avascular tumor imaging with x-ray phase-contrast micro-CT in-line holography

To assess the feasibility of small soft tissue avascular tumor micro-CT imaging with x-ray phase-contrast in-line holography, we have studied micro-CT imaging with in-line geometry of small spheroidal avascular tumor models with quiescent cell core (< 250 mum) and various distributions of the pro...

Full description

Saved in:
Bibliographic Details
Published inProceedings of SPIE, the international society for optical engineering Vol. 6913; p. 69133z
Main Authors Nesterets, Yakov, Gureyev, Tim, Stevenson, Andrew, Pogany, Andrew, Wilkins, Steve, Kincaid, Russell, Ye, Hongwei, Vogelsang, Levon, Lipson, Edward, Coman, Ioana, Fourmaux, Sylvain, Kieffer, Jean-Claude, Krol, Andrzej
Format Journal Article
LanguageEnglish
Published United States 01.01.2008
Online AccessGet more information

Cover

Abstract To assess the feasibility of small soft tissue avascular tumor micro-CT imaging with x-ray phase-contrast in-line holography, we have studied micro-CT imaging with in-line geometry of small spheroidal avascular tumor models with quiescent cell core (< 250 mum) and various distributions of the proliferating cell density (PCD) forming the outer shell. We have simulated imaging with an ultrafast laser-based x-ray source with a Mo target. We observe phase-contrast enhancement of the tumor boundaries in the reconstructed transaxial images, resulting in improved detection of small soft tissue tumors, providing that the PCD density gradient is sufficiently large.
AbstractList To assess the feasibility of small soft tissue avascular tumor micro-CT imaging with x-ray phase-contrast in-line holography, we have studied micro-CT imaging with in-line geometry of small spheroidal avascular tumor models with quiescent cell core (< 250 mum) and various distributions of the proliferating cell density (PCD) forming the outer shell. We have simulated imaging with an ultrafast laser-based x-ray source with a Mo target. We observe phase-contrast enhancement of the tumor boundaries in the reconstructed transaxial images, resulting in improved detection of small soft tissue tumors, providing that the PCD density gradient is sufficiently large.
Author Gureyev, Tim
Krol, Andrzej
Nesterets, Yakov
Stevenson, Andrew
Wilkins, Steve
Coman, Ioana
Pogany, Andrew
Lipson, Edward
Vogelsang, Levon
Ye, Hongwei
Kincaid, Russell
Kieffer, Jean-Claude
Fourmaux, Sylvain
Author_xml – sequence: 1
  givenname: Yakov
  surname: Nesterets
  fullname: Nesterets, Yakov
  organization: CSIRO Manufacturing and Materials Technology, Clayton South, VIC, Australia, 3169
– sequence: 2
  givenname: Tim
  surname: Gureyev
  fullname: Gureyev, Tim
– sequence: 3
  givenname: Andrew
  surname: Stevenson
  fullname: Stevenson, Andrew
– sequence: 4
  givenname: Andrew
  surname: Pogany
  fullname: Pogany, Andrew
– sequence: 5
  givenname: Steve
  surname: Wilkins
  fullname: Wilkins, Steve
– sequence: 6
  givenname: Russell
  surname: Kincaid
  fullname: Kincaid, Russell
– sequence: 7
  givenname: Hongwei
  surname: Ye
  fullname: Ye, Hongwei
– sequence: 8
  givenname: Levon
  surname: Vogelsang
  fullname: Vogelsang, Levon
– sequence: 9
  givenname: Edward
  surname: Lipson
  fullname: Lipson, Edward
– sequence: 10
  givenname: Ioana
  surname: Coman
  fullname: Coman, Ioana
– sequence: 11
  givenname: Sylvain
  surname: Fourmaux
  fullname: Fourmaux, Sylvain
– sequence: 12
  givenname: Jean-Claude
  surname: Kieffer
  fullname: Kieffer, Jean-Claude
– sequence: 13
  givenname: Andrzej
  surname: Krol
  fullname: Krol, Andrzej
BackLink https://www.ncbi.nlm.nih.gov/pubmed/20052303$$D View this record in MEDLINE/PubMed
BookMark eNo1j8tKxDAUQLMYcR668AckP5Axr_amSxl8wYALR3BXMpmkjbRNSVK1f6-grs7ucM4aLYYwWISuGN0yxuCG8S0Ah5It0IpyAAKqfFuidUrvlHJVQHWOlpzSggsqVqh-CS7j7FOaLE697jqsP3QyU6cjzlMfIva9bvzQ4E-fW_xFop7x2OpkiQlDjjpl3HsTA9kdsB9I5weL29CFJuqxnS_QmdNdspd_3KDX-7vD7pHsnx-edrd7YoSSmQhtjVOisM5AKVRVSi0rAU5VlbJWScqFM6ooxRGslBSEZlBKEIUCd3JG8g26_vWO07G3p3qMP9lxrv9P-Tf3TlSW
CitedBy_id crossref_primary_10_1155_2021_7711028
crossref_primary_10_1186_1471_2407_10_589
crossref_primary_10_4103_ijri_IJRI_39_20
ContentType Journal Article
DBID NPM
DOI 10.1117/12.772761
DatabaseName PubMed
DatabaseTitle PubMed
DatabaseTitleList PubMed
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod no_fulltext_linktorsrc
Discipline Engineering
ExternalDocumentID 20052303
Genre Journal Article
GrantInformation_xml – fundername: NIBIB NIH HHS
  grantid: R21 EB005055
– fundername: NIBIB NIH HHS
  grantid: R21 EB005055-02
GroupedDBID 29O
4.4
5SJ
ACGFS
AFFNX
ALMA_UNASSIGNED_HOLDINGS
EBS
EJD
F5P
FQ0
NPM
R.2
RNS
RSJ
SPBNH
UT2
ID FETCH-LOGICAL-c384t-3aecf835efc7638964a4937f8998ee84023fc8563b7e44073a176473587fdfc42
ISSN 0277-786X
IngestDate Thu Nov 24 21:50:48 EST 2022
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed false
IsScholarly true
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c384t-3aecf835efc7638964a4937f8998ee84023fc8563b7e44073a176473587fdfc42
OpenAccessLink https://europepmc.org/articles/pmc2801438?pdf=render
PMID 20052303
ParticipantIDs pubmed_primary_20052303
PublicationCentury 2000
PublicationDate 2008-01-01
PublicationDateYYYYMMDD 2008-01-01
PublicationDate_xml – month: 01
  year: 2008
  text: 2008-01-01
  day: 01
PublicationDecade 2000
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Proceedings of SPIE, the international society for optical engineering
PublicationTitleAlternate Proc SPIE Int Soc Opt Eng
PublicationYear 2008
References 16199495 - Biophys J. 2005 Dec;89(6):3884-94
10847379 - J Digit Imaging. 2000 May;13(2 Suppl 1):121-6
12766293 - Igaku Butsuri. 2002;22(1):21-9
15191283 - Med Phys. 2004 May;31(5):997-1002
17040992 - Biophys J. 2007 Jan 1;92(1):356-65
14655935 - Med Phys. 2003 Nov;30(11):2888-96
11972369 - J Synchrotron Radiat. 2002 May 1;9(Pt 3):148-53
References_xml
SSID ssj0028579
Score 1.9588928
Snippet To assess the feasibility of small soft tissue avascular tumor micro-CT imaging with x-ray phase-contrast in-line holography, we have studied micro-CT imaging...
SourceID pubmed
SourceType Index Database
StartPage 69133z
Title Soft tissue small avascular tumor imaging with x-ray phase-contrast micro-CT in-line holography
URI https://www.ncbi.nlm.nih.gov/pubmed/20052303
Volume 6913
hasFullText
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3fT9swELYKexkPiG3A-LHJD3urDDR24-QRIRCbtAmprQRPlevYgFCaak0R4i_iz-TOdtK0GgL2EqW2Gjm-L-e78-c7Qn5EXaUjyy1TNhoxER8ZlnKdMXCZbZpJWNMtnh3-_Sc-H4hfl93LVuupwVqalaMD_fjPcyX_I1VoA7niKdl3SLZ-KDTAPcgXriBhuL5Jxj3Qoe3STV17muMms6qZpeUsR6p57qsQuXDrA_urMJYBCxdzFHU1Lds5MvLYSb99O2bO5LxZTGMdDNeLeqFz3I_exU9Ho0Sz9XYhqDht0ECLiY-Um3nSw8bGFPzLlA5GV-quuK-ZQDNAF8yEB1IdAXLV18LxsAYLE7V6cQ0abam9CmQkjUCG13e4mywTV9iwVs5x2uEN_Yo_-eMLqt8lD4gOwF-QPsF7AwKT3GEg8mFw_nrvUhbuqmuFrMAQscAqRoWCY590fU7H6gVCBisY0WE9Hsw6HZ6x5ME4S6a_QdaDC0KPPZ4-kZYZfyZrjcSUX8gQkUU9sqhDFq2RRR2yaEAWRWRRhyy6iCxaIYsGZNE5sjbJ4Oy0f3LOQikOpnkiSsaV0RaMdWO1RBs3FkqAYWvRWzcmEWD5WZ10Yz6SRghYNlRHxljVOpE2s1pEW2R1XIzNV0Kt0MZmYNpbbkSamTQRWayN5FKBYsg6O2Tbz85w4vOtDKt5232xZ498nCNqn3yw8IGbb2AtlqPvTlTPQQltjw
link.rule.ids 786
linkProvider National Library of Medicine
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Soft+tissue+small+avascular+tumor+imaging+with+x-ray+phase-contrast+micro-CT+in-line+holography&rft.jtitle=Proceedings+of+SPIE%2C+the+international+society+for+optical+engineering&rft.au=Nesterets%2C+Yakov&rft.au=Gureyev%2C+Tim&rft.au=Stevenson%2C+Andrew&rft.au=Pogany%2C+Andrew&rft.date=2008-01-01&rft.issn=0277-786X&rft.volume=6913&rft.spage=69133z&rft_id=info:doi/10.1117%2F12.772761&rft_id=info%3Apmid%2F20052303&rft_id=info%3Apmid%2F20052303&rft.externalDocID=20052303
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0277-786X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0277-786X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0277-786X&client=summon