Diagnostic criteria for small fibre neuropathy in clinical practice and research

Definitive diagnostic criteria for small fibre neuropathy have yet to be established, with implications both for clinical practice and for the design of clinical trials. Devigili et al. demonstrate that a combined approach – with clinical, functional and structural assessment of small nerve fibres –...

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Published inBrain (London, England : 1878) Vol. 142; no. 12; pp. 3728 - 3736
Main Authors Devigili, Grazia, Rinaldo, Sara, Lombardi, Raffaella, Cazzato, Daniele, Marchi, Margherita, Salvi, Erika, Eleopra, Roberto, Lauria, Giuseppe
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.12.2019
Subjects
Adult
Aged
Electrodiagnosis
Female
Humans
Male
Middle Aged
Nerve Fibers - pathology
Nerve Fibers - physiology
Neural Conduction - physiology
Original
Retrospective Studies
Sensory Thresholds - physiology
Skin - pathology
Small Fiber Neuropathy - diagnosis
Small Fiber Neuropathy - pathology
Small Fiber Neuropathy - physiopathology
Young Adult
diagnostic criteria
neuropathic pain
quantitative sensory testing
skin biopsy
small fibre neuropathy
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Summary:Definitive diagnostic criteria for small fibre neuropathy have yet to be established, with implications both for clinical practice and for the design of clinical trials. Devigili et al. demonstrate that a combined approach – with clinical, functional and structural assessment of small nerve fibres – improves the reliability of diagnosis.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0006-8950
1460-2156
1460-2156
DOI:10.1093/brain/awz333