Ultrasound- and Negative Pressure-assisted Fractional Precipitation of Paclitaxel from Taxus chinensis

• Published in: Biotechnology and bioprocess engineering Vol. 28; no. 2; pp. 336 - 344
• Main Authors: Shin, Eun-Ju, Kim, Jin-Hyun
• Format: Journal Article
• Language: English
• Published: Seoul The Korean Society for Biotechnology and Bioengineering 01.04.2023; Springer Nature B.V; 한국생물공학회
• Subjects: activation energy; Biotechnology; Chemistry; Chemistry and Materials Science; Diffusion coefficient; Industrial and Production Engineering; Paclitaxel; Precipitates; Pressure; Rate constants; Research Paper; Taxus chinensis; Taxus wallichiana var. chinensis; Ultrasonic imaging; ultrasonics; Ultrasound; 생물공학; paclitaxel; negative pressure; ultrasound; fractional precipitation; synergistic effect

The effect of ultrasound and negative pressure on the efficiency of fractional precipitation of paclitaxel derived from Taxus chinensis was investigated. Introducing both ultrasound and negative pressure during fractional precipitation resulted in a precipitation time that was 2 times faster than th...