Small-Cell Lung Cancer and Necrolytic Migratory Erythema

To the Editor: Necrolytic migratory erythema is a rare inflammatory dermatosis, first described by Becker et al., 1 which occurs in 70% of patients with the glucagonoma syndrome. 2 Its clinical features are polymorphic mucocutaneous manifestations, encompassing multiple annular erythematous scaling...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 359; no. 25; pp. 2731 - 2732
Main Authors Mignogna, Michele Davide, Satriano, Alfredo Rocco, Fortuna, Giulio
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 18.12.2008
Subjects
Aged
Erythema - etiology
Erythema - pathology
Fatal Outcome
Humans
Lung Neoplasms - complications
Male
Mucositis - etiology
Mucositis - pathology
Paraneoplastic Syndromes - pathology
Small Cell Lung Carcinoma - complications
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ISSN0028-4793
1533-4406
1533-4406
DOI10.1056/NEJMc0805992

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Summary:To the Editor: Necrolytic migratory erythema is a rare inflammatory dermatosis, first described by Becker et al., 1 which occurs in 70% of patients with the glucagonoma syndrome. 2 Its clinical features are polymorphic mucocutaneous manifestations, encompassing multiple annular erythematous scaling and crusting patches with hyperpigmentation. These lesions can affect the entire body with a predilection for the perineum, buttocks, groin, abdomen, and limbs — in other words, areas that are subject to increased pressure and friction. 2 , 3 The only two reported oral findings are angular cheilitis and atrophic glossitis. 2 – 5 A 73-year-old man was referred to our oral medicine unit for . . .
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMc0805992