A coherent model for turbid imaging with confocal microscopy

We present an engineering model of coherent imaging within a turbid volume, such as human tissues, with a confocal microscope. The model is built to analyze the statistical effect of aberrations and multiply scattered light on the resulting image. Numerical modeling of theory is compared with experi...

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Bibliographic Details
Published inBiomedical optics express Vol. 4; no. 4; pp. 500 - 513
Main Authors Glazowski, Christopher E, Zavislan, James
Format Journal Article
LanguageEnglish
Published United States Optical Society of America 01.04.2013
Subjects
Optics of Tissue and Turbid Media
(110.0113) Imaging through turbid media
(170.3660) Light propagation in tissues
(170.1790) Confocal microscopy
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Summary:We present an engineering model of coherent imaging within a turbid volume, such as human tissues, with a confocal microscope. The model is built to analyze the statistical effect of aberrations and multiply scattered light on the resulting image. Numerical modeling of theory is compared with experimental results. We describe the construction of a stable phantom that represents the statistical effect of object turbidity on the image recorded. The model and phantom can serve as basis for system optimization in turbid imaging.
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ISSN:2156-7085
2156-7085
DOI:10.1364/BOE.4.000500