Sleep apnea assessment using declination duration-based global metrics from unobtrusive fiber optic sensors

• Published in: Physiological measurement Vol. 40; no. 7; p. 075005
• Main Authors: Hsu, Ming-Hung, Fang, Shih-Chin, Wang, Fu-Tai, Chan, Hsiao-Lung, Huang, Hsiu-En, Yang, Shu-Chen
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 30.07.2019
• Subjects: Adult; apnea hypopnea index; fiber optic sensor; Humans; Linear Models; Monitoring, Physiologic - instrumentation; Optical Fibers; polysomnography; Pressure; Respiration; respiratory declination; Signal-To-Noise Ratio; Sleep Apnea Syndromes - diagnosis; Sleep Apnea Syndromes - physiopathology; unobtrusive measurement
• ISSN: 0967-3334; 1361-6579; 1361-6579
• DOI: 10.1088/1361-6579/ab21b5

Objective: Sufficient sleep helps to restore the immune, nervous and cardiovascular systems, but is sometimes disturbed by sleep apnea (SA). The early diagnosis of sleep apnea is beneficial for the prevention of diseases. Polysomnography (PSG) recording provides comprehensive data for such assessment, but is not suitable for use at home due to discomfort during measurement and the difficulty of identification. This study proposes an unobtrusive measurement process by placing fiber optic sensors (FOSs) in a pillow (head-neck) or a bed mattress (thoracic-dorsal). Approach: We test two approaches: drop degrees from the baseline to validate the capability of catching respiratory drops, and linear regression models based on a new global measure, the percentage of the total duration of respiratory declination (PTDRD), to estimate the hand-scored apnea/hypopnea index (AHI). Main results: Based on data recorded from 63 adults, the drop degrees derived from respiratory signals exhibited statistical differences among central sleep apnea (CSA), obstructive sleep apnea (OSA) and normal breathing. The regression models based on the PTDRDs derived from head-neck FOS and thoracic-dorsal FOS also achieved good agreement with manually scored AHIs in Bland-Altman plots as well as oronasal airflow and thoracic wall movement. Significance: The aforementioned performance demonstrates the capability of the FOS measurement and the efficacy of the PTDRD metrics for SA assessment.