A unique circulating inhibitor with specificity for coagulation factor X

An 84-year-old woman presented with extensive cutaneous and gastrointestinal bleeding. Initial laboratory studies revealed a prolonged prothrombin time and activated partial thromboplastin time. Further investigations revealed a circulating anticoagulant with specificity for factor X. The patient�...

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Bibliographic Details
Published inThe American journal of medicine Vol. 93; no. 3; pp. 343 - 346
Main Authors Lankiewicz, Michael W., Bell, William R.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.09.1992
Elsevier Sequoia S.A
Subjects
Aged
Aged, 80 and over
Blood Coagulation - physiology
Circulatory system
Diagnosis, Differential
Factor X Deficiency - blood
Factor X Deficiency - diagnosis
Factor X Deficiency - etiology
Female
Hemorrhage
Humans
Vitamins
Women
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Summary:An 84-year-old woman presented with extensive cutaneous and gastrointestinal bleeding. Initial laboratory studies revealed a prolonged prothrombin time and activated partial thromboplastin time. Further investigations revealed a circulating anticoagulant with specificity for factor X. The patient's hemorrhage resolved with supportive measures only. Approximately 11 months after presentation, the inhibitor disappeared.
Bibliography:ObjectType-Case Study-3
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-2
ISSN:0002-9343
1555-7162
DOI:10.1016/0002-9343(92)90244-6