Evaluation of a health system-wide pharmacist-driven emergency department laboratory follow-up and antimicrobial management program

• Published in: The American journal of emergency medicine Vol. 38; no. 12; pp. 2591 - 2595
• Main Authors: Wu, Janet Y., Balmat, Ryan, Kahle, Maria L., Blynn, Meredith, Hipp, Rachel, Podolsky, Seth, Fertel, Baruch S.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2020; Elsevier Limited
• Subjects: Aftercare - organization & administration; Anti-Infective Agents - therapeutic use; Antimicrobial agents; Antimicrobial Stewardship; Blood tests; Candidiasis; Clinical outcomes; Culture follow-up; Culture Techniques; Deprescriptions; Drug stores; Drug Substitution; Electronic medical records; Emergency department; Emergency medical care; Emergency Service, Hospital; Hospitals; Humans; Infectious diseases; Intervention; Laboratories; Multi-Institutional Systems; Patient education; Pharmacists; Pharyngitis - drug therapy; Pharyngitis - microbiology; Professional Role; Sexually Transmitted Diseases - drug therapy; Sexually Transmitted Diseases - microbiology; Transition of care; Urinary Tract Infections - drug therapy; Urinary Tract Infections - microbiology; Vagina; Vaginosis; Wound Infection - drug therapy; Wound Infection - microbiology; Culture follow-up; Antimicrobial stewardship; Emergency department; Infectious diseases; Transition of care
• ISSN: 0735-6757; 1532-8171
• DOI: 10.1016/j.ajem.2019.12.052

Emergency Department (ED) follow-up programs ensure that cultures, laboratory studies, and empiric antimicrobials are appropriately managed post-discharge. We sought to provide a comprehensive assessment of a pharmacist-driven laboratory follow-up process in a large, integrated health system. A retrospective, observational review of 13 EDs was conducted. Patients were included if they had a laboratory study sent from the ED between December 1, 2017 and May 31, 2018 that did not result while the patient was in the ED. Microbiology results analyzed were urine, wound, respiratory, stool, throat, bacterial vaginosis, vaginal candidiasis, and sexually transmitted infections (STI). Examples of laboratory results assessed were metabolic panels and drug levels. The primary objective was to quantify the number of interventions made by pharmacists. During a 6-month period, pharmacists reviewed 9107 microbiology results and 6211 laboratory results. The majority of results were urine cultures (3998, 50.6%) followed by STI results (1198, 15.2%). Of 7663 encounters, 39.8% required interventions and/or follow-up with a total of 3049 interventions made and 3333 patients educated. The most common interventions were initiation of therapy (1629, 53.4%), change in medication (505, 16.6%), and follow-up with a clinician (322, 10.6%). Pharmacists reviewed microbiology results and completed interventions in a median of 25.3 h from the time the result was received in the electronic health record. Almost 40% of ED encounters required an intervention after discharge. A pharmacist led laboratory follow-up program is an important adjunct to facilitating stewardship and culture management in the ED.