Antidepressant-induced hypomania in obsessive-compulsive disorder

Out of ten consecutive patients with DSM-III-R obsessive-compulsive disorder without any previous history of bipolarity, three patients showed antidepressant-induced hypomania (clomipramine, one patient; fluvoxamine, two patients) within the first 5 to 8 weeks of the drug treatment. These data suppo...

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Bibliographic Details
Published inInternational clinical psychopharmacology Vol. 11; no. 3; p. 203
Main Authors Rihmer, Z, Barsi, J, Belsõ, N, Pestality, P, György, S
Format Journal Article
LanguageEnglish
Published England 01.09.1996
Subjects
Adolescent
Adult
Affective Disorders, Psychotic - chemically induced
Antidepressive Agents - adverse effects
Clomipramine - adverse effects
Clomipramine - therapeutic use
Female
Fluvoxamine - adverse effects
Fluvoxamine - therapeutic use
Humans
Male
Middle Aged
Obsessive-Compulsive Disorder - drug therapy
Serotonin Uptake Inhibitors - adverse effects
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Summary:Out of ten consecutive patients with DSM-III-R obsessive-compulsive disorder without any previous history of bipolarity, three patients showed antidepressant-induced hypomania (clomipramine, one patient; fluvoxamine, two patients) within the first 5 to 8 weeks of the drug treatment. These data support the previous results on a strong association between obsessive-compulsive disorder and bipolar affective illness.
ISSN:0268-1315
DOI:10.1097/00004850-199609000-00008